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Class II Microcins
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Vassiliadis, Gaelle; Destoumieux-garzon, Delphine; Peduzzi, Jean.
Class II microcins are 4.9- to 8.9-kDa polypeptides produced by and active against enterobacteria. They are classified into two subfamilies according to their structure and their gene cluster arrangement. While class ha microcins undergo no posttranslational modification, class Jib rnicrocins show a conserved C-terminal sequence that carries a salmochelin-like siderophore motif as a posttranslational modification. Aside from this C-terminal end, which is the signature of class IIb microcins, some sequence similarities can be observed within and between class II subclasses, suggesting the existence of common ancestors. Their mechanisms of action are still under investigation, but several class II microcins use inner membrane proteins as cellular targets,...
Tipo: Text
Ano: 2011
URL: http://archimer.ifremer.fr/doc/00073/18386/16447.pdf