Consulta: creatorFacets:"Vila,L."
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Ginseng administration protects skeletal muscle from oxidative stress induced by acute exercise in rats
Provedor de dados: 56
Autores: Voces,J.; Cabral de Oliveira,A.C.; Prieto,J.G.; Vila,L.; Perez,A.C.; Duarte,I.D.G.; Alvarez,A.I.
Enzymatic activity was analyzed in the soleus, gastrocnemius (red and white) and plantaris muscles of acutely exercised rats after long-term administration of Panax ginseng extract in order to evaluate the protective role of ginseng against skeletal muscle oxidation. Ginseng extract (3, 10, 100, or 500 mg/kg) was administered orally for three months to male Wistar rats weighing 200 ± 50 g before exercise and to non-exercised rats (N = 8/group). The results showed a membrane stabilizing capacity of the extract since mitochondrial function measured on the basis of citrate synthase and 3-hydroxyacyl-CoA dehydrogenase activities was reduced, on average, by 20% (P &lt; 0.05) after exercise but the activities remained unchanged in animals treated with a ginseng...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Panax ginseng; Exercise; Free radicals; Lipid peroxidation; Glutathione status; Mitochondria.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001200012