Consulta: creatorFacets:"Yamamoto,Mihoko"
Registros recuperados: 4
Data/hora: 10/06/2024 09:00:45

A rare case of Acute Lymphocytic Leukemia (ALL) presenting with double Philadelphia chromosome: relapse or secondary leukemia?
Provedor de dados: Genetics and Molecular Biology
Autores: Campos,Mireille Guimarães Vaz de; Chauffaille,Maria de Lourdes L. Ferrari; Rodrigues,Celso Arrais; Krum,Everson A.; Yamamoto,Mihoko.
The Philadelphia chromosome is observed in 5% of pediatric acute lymphocytic leukemia (ALL) and in 25% to 50% of adult ALL cases, and is associated with poor prognosis. Double Ph in a hyperdiploid karyotype is common in chronic myeloid leukemia (CML), but rarely found in ALL. We report here the case of a girl diagnosed with ALL at 7 years of age. After treatment with the pediatric protocol BFM 83 for ALL, she stayed in continuous complete remission for nine years. At age 19, she was re-admitted with a white blood cell count of 6.8 x 10(9)/L with 3% blasts, and a platelet count of 65 x 109/L. Bone marrow aspirate showed 92.6% lymphoid blast cells, and chromosome analysis after G-banding revealed the karyotype...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Relapsed acute lymphocytic leukemia; Double Philadelphia chromosome.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300006

Detection of trisomy 12 by fluorescent in situ hybridization (FISH) in chronic lymphocytic leukemia
Provedor de dados: Genetics and Molecular Biology
Autores: Chauffaille,Maria de Lourdes L.F.; Marques,Eliana Azevedo; Oliveira,Jose Salvador Rodrigues de; Rodrigues,Maria Madalena; Figueiredo,Maria Stella; Romeo,Maura; Yamamoto,Mihoko; Kerbauy,José.
Chronic lymphocytic leukemia (CLL) presents a varying incidence of karyotypic abnormalities whose detection is complicated by difficulties in obtaining mitosis for analysis in this type of mature lymphocyte disorder. Since the introduction of molecular cytogenetics (FISH = fluorescent in situ hybridization), applying centromeric probes for chromosome 12 has made it possible to detect a higher percentage of trisomy 12 cases. The objective of the present study was to detect trisomy 12 by FISH (alpha satellite probe) in 13 patients with CLL whose karyotypes by G-banding were either normal or inadequate. Using this method trisomy 12 was detected in three patients in a percentage of positive cells varying from 55.5% to 79%, showing that FISH is a sensitive and...
Tipo: Info:eu-repo/semantics/article
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000300005

Human neutrophil alloantigens systems
Provedor de dados: Anais da Academia Brasileira de Ciências
Autores: Moritz,Elyse; Norcia,Ângela M. M. I.; Cardone,José D. B.; Kuwano,Sachie T.; Chiba,Akemi K.; Yamamoto,Mihoko; Bordin,José O.
Neutrophil alloantigens are involved in a variety of clinical conditions including immune neutropenias, transfusion-related acute lung injury (TRALI), refractoriness to granulocyte transfusions and febrile transfusion reactions. In the last decade, considerable progress has been made in the characterization of the implicated antigens. Currently, seven antigens are assigned to five human neutrophil antigen (HNA) systems. The HNA-1a, HNA-1b and HNA-1c antigens have been identified as polymorphic forms of the neutrophil Fcγ receptor IIIb (CD16b), encoded by three alleles. Recently, the primary structure of the HNA-2a antigen was elucidated and the HNA-2a-bearing glycoprotein was identified as a member of the Ly-6/uPAR superfamily, which has been clustered as...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Neutrophil antigens; Blood transfusion; Alloimmunization; Transfusion reaction; Neutropenia.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300019

Septic arthritis as the first sign of Candida tropicalis fungaemia in an acute lymphoid leukemia patient
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Vicari,Perla; Pinheiro,Ronald Feitosa; Chauffaille,Maria de Lourdes Lopes Ferrari; Yamamoto,Mihoko; Figueiredo,Maria Stella.
Fungal infections caused by Candida species have increased in incidence during the past two decades in England, North America and Europe. Candidal arthritis is rare in patients who are not intravenous drug users or are who not using a prostheses. We report the case of a 24-year-old man with acute lymphoid leukemia, who developed Candida tropicalis arthritis during an aplastic period after chemotherapy. This is the eighth case described in the literature of C. tropicalis causing arthritis without intra-articular inoculation. We call attention to an unusual first sign of fungal infection: septic arthritis without intra-articular inoculation. However, this case differs from the other seven, since despite therapy a fast and lethal evolution was observed. We...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Septic arthritis; Candida tropicalis; Fungal infections; Candida tropicalis arthritis; Systemic candidiasis.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600012