Consulta: creatorFacets:"Zheng,Xiao"
Registros recuperados: 1
Data/hora: 10/06/2024 01:20:44

Association of PRKAA1 gene polymorphisms with chronic hepatitis B virus infection in Chinese Han population
Provedor de dados: 55
Autores: Yuan,Jun; Zhang,Yan; Yan,Fu-tang; Zheng,Xiao.
ABSTRACT  Objective: Studies have indicated that AMPK play critical roles in the regulation of innate immunity and inflammatory responses. However, the role of the polymorphisms of PRKAA1 gene in immune-response to infectious organisms remains unknown. To evaluate the potential role of PRKAA1/AMPKα1 in the immune-response to HBV, we conducted this case-control study.  Methods: We recruited 276 patients (145 men and 131 women; average age, 51.6 years) with chronic HBV infection (CHB) and 303 healthy controls (166 men and 137 women; average age, 54.2 years). All the subjects were unrelated individuals of Chinese Han Population. Three SNPs of PRKAA1gene were tested.  Results: Rs1002424 polymorphism showed significant difference in the allele frequencies, but...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: HBV; PRKAA1 gene; SNP; Association study.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600564