Consulta: subjectFacets:"Albendazole"
Registros recuperados: 4
Data/hora: 08/06/2024 11:59:52

Trichostrongylus and Haemonchus anthelmintic resistance in naturally infected sheep from southern Brazil
Provedor de dados: 42
Autores: KLAUCK,VANDERLEI; PAZINATO,RAFAEL; LOPES,LEANDRO S.; CUCCO,DIEGO C.; LIMA,HORACIO L. DE; VOLPATO,ANDREIA; RADAVELLI,WILLIAN M.; STEFANI,LENITA C.M.; SILVA,ALEKSANDRO S. DA.
The anthelmintic resistance in small ruminants is a common problem and concern worldwide. The aim of this study was to verify anthelmintic treatment efficacy in naturally infected sheep. This study was conducted on nine herds that used the same anthelmintic management for over a year. In each farm, the animals were divided into two groups: untreated control group (n = 5) and treated (n = 10) according to the number of eggs per gram of feces (EPG). The treatment effect was checked based on EPG results and larval culture performed before treatment and 10 days after treatment. Significant differences were not observed (P&gt; 0.05) on EPG results between untreated and treated groups. The coproculture showed that the animals were infected primarily byHaemonchus...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Anthelmintic resistance; Albendazole; Closantel; Levamizol; Helminths.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000200777

Sensory evaluation of albendazole suspensions
Provedor de dados: 52
Autores: Fregonezi-Nery,Marlene Maria; Prudencio-Ferreira,Sandra Helena; Kedor,Érika Maria Rosa; Baracat,Marcela Maria; Brinholi,Francis Fregonezi.
Sensory analysis was used in the albendazole suspension stability study. Three formulations were prepared and stored for 1, 3, and 6 months at 4 ±1, 26 ±1, 37, 50 and 65 ºC. Samples were evaluated through the difference from control sensory test using 24 trained judges in individual cabins. Although albendazole content was not altered in the conditions studied, sensory test showed differences between control and stored samples, except for one of the formulations stored under refrigeration for one month. These results have shown that the sensory evaluation is an important tool for quality control of pharmaceutical preparations, in association with chemical, physicochemical and microbiological tests.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Albendazole; Sensory analysis; High performance liquid chromatography.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000600009

Albendazole metabolism in patients with neurocysticercosis: antipyrine as a multifunctional marker drug of cytochrome P450
Provedor de dados: 56
Autores: Marques,M.P.; Takayanagui,O.M.; Lanchote,V.L.
The present study investigates the isoform(s) of cytochrome P450 (CYP) involved in the metabolism of albendazole sulfoxide (ASOX) to albendazole sulfone (ASON) in patients with neurocysticercosis using antipyrine as a multifunctional marker drug. The study was conducted on 11 patients with neurocysticercosis treated with a multiple dose regimen of albendazole for 8 days (5 mg/kg every 8 h). On the 5th day of albendazole treatment, 500 mg antipyrine was administered po. Blood and urine samples were collected up to 72 h after antipyrine administration. Plasma concentrations of (+)-ASOX, (-)-ASOX and ASON were determined by HPLC using a chiral phase column and detection by fluorescence. The apparent clearance (CL/f) of ASON and of the (+) and (-)-ASOX...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Albendazole; Cysticercosis; Enantiomers; Antipyrine; Cytochrome P450; CYP; Patients.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000200016

Associação de imunoestimulante com anti-helmíntico no tratamento da verminose em ovinos
Provedor de dados: 65
Autores: Martins,Maria de Fátima Monteiro; Garcia,Maurício; Chate,Sabrina Caruso; Tavolari,Fabrízia Aparecida; Teixeira,Raffaella Bertoni Cavalcanti; Mertens Júnior,Luis Roberto; Silva,Marilene Machado; Scheibel,Monika; Abel,Lúcia Jamli.
Este estudo teve como objetivo verificar a eficiência do uso de imunoestimulante associado a anti-helmíntico no tratamento das helmintoses de ovinos. Os animais do grupo I (n=29) receberam o anti-helmíntico albendazole (11mg kg-1) em administração única e o imunoestimulante composto de Propionibacterium granulosum (16ug kg-1) e lipopolissacarídeo (LPS) de Escherichia coli (1,2ug kg-1) em duas doses com intervalo de 48 horas e os animais do grupo II (n=29) receberam o anti-helmíntico albendazole (11mg kg-1). Amostras foram colhidas semanalmente durante 28 dias para a realização da contagem total e diferencial de leucócitos, hematócrito e contagem de ovos por grama de fezes (OPG). Os animais que receberam imunoestimulante associado a anti-helmíntico...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Helmintos; Albendazole; LPS; Propionibacterium granulosum; Hemograma.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782012001200020