Consulta: subjectFacets:"Animal models of anxiety"
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Data/hora: 12/06/2024 10:42:36

Animal models of anxiety: an ethological perspective
Provedor de dados: Brazilian Journal of Medical and Biological Research
In the field of anxiety research, animal models are used as screening tools in the search for compounds with therapeutic potential and as simulations for research on mechanisms underlying emotional behaviour. However, a solely pharmacological approach to the validation of such tests has resulted in distinct problems with their applicability to systems other than those involving the benzodiazepine/GABAA receptor complex. In this context, recent developments in our understanding of mammalian defensive behaviour have not only prompted the development of new models but also attempts to refine existing ones. The present review focuses on the application of ethological techniques to one of the most widely used animal models of anxiety, the elevated plus-maze...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Animal models of anxiety; Ethology; Defence; Risk assessment; Plus-maze; Behavioural profiling; Pharmacology.
Ano: 1997
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300002