Consulta: subjectFacets:"Anticoagulant drugs"
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Data/hora: 16/06/2024 08:52:43

Heterofucans from Dictyota menstrualis have anticoagulant activity
Provedor de dados: 56
Autores: Albuquerque,I.R.L.; Queiroz,K.C.S.; Alves,L.G.; Santos,E.A.; Leite,E.L.; Rocha,H.A.O.
Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins. Plant fucans have several biological activities, including anticoagulant and antithrombotic, related to the structural and chemical composition of polysaccharides. We have extracted sulfated polysaccharides from the brown seaweed Dictyota menstrualis by proteolytic digestion, followed by separation into 5 fractions by sequential acetone precipitation. Gel electrophoresis using 0.05 M 1,3-diaminopropane-acetate buffer, pH 9.0, stained with 0.1% toluidine blue, showed the presence of sulfated polysaccharides in all fractions. The chemical analyses demonstrated that all...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Fucan; Fucoidan; Anticoagulant drugs; Brown algae; Antithrombotic agents.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200002