Consulta: subjectFacets:"Antifertility"
Registros recuperados: 2
Data/hora: 16/06/2024 01:37:46

Extracts of Azadirachta indica and Melia azedarach seeds inhibit folliculogenesis in albino rats
Provedor de dados: 56
Autores: Roop,J.K.; Dhaliwal,P.K.; Guraya,S.S.
The seed oil of Azadirachta indica A. Juss (neem) is used in traditional medicine for its antidiabetic, spermicidal, antifertility, antibacterial, and wound healing properties. The present study was undertaken to investigate the quantitative aspects of follicular development in cyclic female albino rats (135 ± 10 g; 8 groups with 6 animals in each group) after oral administration of polar (PF) and non-polar (NPF) fractions of A. indica seed extract at 3 and 6 mg kg body weight-1 day-1 and Melia azedarach Linn. (dharek) seed extract at 24 mg kg body weight-1 day-1 for 18 days. The extracts were prepared using a flash evaporator at 35°C and then dissolved in olive oil to prepare doses on a per kg body weight basis. There was a significant reduction (P =...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Folliculogenesis; Azadirachta; Melia; Plant products; Antifertility.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600017

Effect of Ethanol Extract of Whole Plant of Trichosanthes cucumerina var. cucumerina L. on Gonadotropins, Ovarian Follicular Kinetics and Estrous Cycle for Screening of Antifertility Activity in Albino Rats
Provedor de dados: 77
Autores: Kage,Devendra N; Malashetty,Vijaykumar B; Seetharam,Y. N; Suresh,P; Patil,Saraswati B.
Ethanol extract of whole plant of Trichosanthes cucumerina L. var. cucumerina was evaluated for antiovulatory activity in adult rats. The ethanol extract at the doses 200 and 400mg/kg body weight (orally) affected the normal estrous cycle showing a significant increase in estrus and metestrus phases and decrease in diestras and proestrus phases. The extract also significantly reduced the number of healthy follicles (Class I-Class VI) and corpora lutea and increased the number of regressing follicles (Stage IA, Stage IB, Stage IIA, and Stage IIB). The protein and glycogen content in the ovaries were significantly reduced in treated rats. The cholesterol level was significantly increased, whereas, the enzyme activities like 3b-HSD and 17b-HSD were...
Tipo: Journal article
Palavras-chave: Trichosanthes cucumerina L. var. cucumerina; Antifertility; Folliculogenesis; Estrous cycle; Gonadotropins; 3 b-HSD; 17 b-HSD activity; Ovarian steroidogenesis.
Ano: 2009
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000100030