Consulta: subjectFacets:"Anxiolytic effect"
Registros recuperados: 1
Data/hora: 04/06/2024 03:52:46

Anterograde effects of a single electroconvulsive shock on inhibitory avoidance and on cued fear conditioning
Provedor de dados: 56
Autores: Oliveira,M.G.M.; Bueno,O.F.A.; Gugliano,E.B.
A single electroconvulsive shock (ECS) or a sham ECS was administered to male 3-4-month-old Wistar rats 1, 2, and 4 h before training in an inhibitory avoidance test and in cued classical fear conditioning (measured by means of freezing time in a new environment). ECS impaired inhibitory avoidance at all times and, at 1 or 2 h before training, reduced freezing time before and after re-presentation of the ECS. These results are interpreted as a transient conditioned stimulus (CS)-induced anxiolytic or analgesic effect lasting about 2 h after a single treatment, in addition to the known amnesic effect of the stimulus. This suggests that the effect of anterograde learning impairment is demonstrated unequivocally only when the analgesic/anxiolytic effect is...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Electroconvulsive shock; Memory; Cued fear conditioning; Inhibitory avoidance; Anxiolytic effect; Analgesic effect.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800009