Consulta: subjectFacets:"Bone marrow transplantation"
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Data/hora: 10/06/2024 06:23:34

Monosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: report of a new case and review of the literature
Provedor de dados: 74
Autores: Otero,Luize; Souza,Daiane Correa de; Tavares,Rita de Cássia; Gomes,Bernadete Evangelho; Padilha,Telma França; Bouzas,Luiz Fernando; Fernandez,Teresa de Souza; Abdelhay,Eliana.
Monosomy 7 arises as a recurrent chromosome aberration in donor cell leukemia after hematopoietic stem cell transplantation. We report a new case of donor cell leukemia with monosomy 7 following HLA-identical allogenic bone marrow transplantation for severe aplastic anemia (SAA). The male patient received a bone marrow graft from his sister, and monosomy 7 was detected only in the XX donor cells, 34 months after transplantation. The patient's bone marrow microenvironment may have played a role in the leukemic transformation of the donor hematopoietic cells.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Monosomy 7; Donor cell leukemia; Bone marrow transplantation; Severe aplastic anemia.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500004

Central venous access through the external jugular vein in children submitted to bone marrow transplantation
Provedor de dados: 52
Autores: Godoy,José Luiz de; Otta,Edson Keity; Miyazaki,Ricardo Atsumori; Bitencourt,Marco Antonio; Pasquini,Ricardo.
Establishment of long-term central venous access is a sine qua non step for bone marrow transplantation in children. Most frequently, long-term central venous access has been obtained via blind percutaneous cannulation of subclavian and internal jugular veins or via internal jugular vein cutdown. In order to avoid some potential minor and major complications associated with the subclavian or internal jugular approaches, the authors describe an easy, simple and safe method for central venous access through an external jugular vein cutdown that should be of interest to readers involved in the field of bone marrow transplantation. It should be also considered for children as well as adults needing central venous access via an external catheter - or totally...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Central venous access; External jugular vein; Bone marrow transplantation; Catheter.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000100007

Polyoma BK virus: an emerging opportunistic infectious agent of the human central nervous system
Provedor de dados: 55
Autores: Silva,Rodrigo Lopes da.
BK virus, a double-stranded DNA virus, is a member of the Polyomaviridae family which is known to infect humans. Clinical evidence of disease is mostly encountered in immunosuppressed individuals such as AIDS patients or those who undergo renal or bone marrow transplantation where complications associated with BKV infection manifest commonly as a polyomavirus nephropathy or hemorrhagic cystitis, respectively. Recent evidence suggests that in addition to the JC virus (the other member of the same family known to be strongly neurotropic and responsible for the progressive multifocal leukoencephalopathy), BK virus can infect and cause clinically relevant disease in the human central nervous system. In this mini-review, an analysis of the literature is made. A...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: BK virus; Bone marrow transplantation; AIDS-related opportunistic infections.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300017

Oral HPV infection in a bone marrow transplantation patient: a case report with atypical clinical presentation and unexpected outcome
Provedor de dados: 55
Autores: Pereira,Claudio Maranhão; Melo,Laura Guimarães; Correa,Maysa Milazzo; Souza,Cármino Antônio; Corrêa,Maria Elvira P.
HPV (Human Papilloma Virus) is one of the most prevalent infections worlwide. Oral HPV infection may be associated with different diseases of oral cavitie. Although oral HPV infection occurs frequently, it rarely causes lesions. An increased rate of oral HPV-induced lesions is observed in people with an impaired immune system. The most common conditions induced by oral HPV infection are focal epithelial hyperplasia, oral condylomas and oral papillomas. We reported a case of oral HPV lesion in a bone marrow transplantation patient with atypical clinical presentation and unexpected outcome.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: HPV; Bone marrow transplantation; Leukemia.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000100018

Comparison of immunoperoxidase and immunofluorescence assays for pp65 cytomegalovirus antigen in immunocompromised patients
Provedor de dados: 55
Autores: Debur,Maria do Carmo; Vidal,Luine R. Rosele; Nogueira,Meri Bordignon; Pereira,Luciane Aparecida; Takahashi,Gislene R.A.; Rotta,Indianara; Almeida,Sérgio Monteiro de; Raboni,Sonia Mara.
We compared the pp65 antigen detection by an in house method (immunoperoxidase assay) and by a commercial kit (immunofluorescence assay) available for cytomegalovirus infection diagnosis in immunocompromised patients. Sixty-four blood samples were analyzed in duplicate for both techniques. Eight-six percent of the samples had concordant qualitative results. The discordant results occurred more frequently in samples with low quantity of positive cells. There were no significant differences with qualitative and quantitative results of the methods.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Immunoperoxidase; Immunofluorescence; Cytomegalovirus; Immunocompromised patients; Bone marrow transplantation; Solid organ transplant.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200014

Angioinvasive pulmonary aspergillosis after allogeneic bone marrow transplantation: clinical and high-resolution computed tomography findings in 12 cases
Provedor de dados: 55
Autores: Gasparetto,Emerson L.; Souza,Carolina A.; Tazoniero,Priscilla; Davaus,Taisa; Escuissato,Dante L.; Marchiori,Edson.
The aim of this study was to present the clinical and high-resolution CT scan findings of angioinvasive pulmonary aspergillosis (APA) in 12 patients who underwent allogeneic bone marrow transplantation (BMT). The CT scans were reviewed by three chest radiologists who assessed the pattern and distribution of findings by consent. There were 7 (58%) female and 5 (42%) male patients, with aging between 5 and 50 years (average of 26 years). All patients were submitted to BMT for the treatment of hematological conditions. The diagnosis of APA was defined between 5 and 373 days after BMT, with average of 111 days. Three cases (25%) were diagnosed in the neutropenic phase after the BMT, five (42%) in the early phase and four patients in the late phase post-BMT....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Invasive pulmonary aspergillosis; Bone marrow transplantation; High-resolution computed tomography.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000100024

Reimmunization after bone marrow transplantation: current recommendations and perspectives
Provedor de dados: 56
Autores: Machado,C.M.
Autologous and allogeneic bone marrow transplantation (BMT) recipients lose immune memory of exposure to infectious agents and vaccines accumulated through a lifetime and therefore need to be revaccinated. Diphtheria toxoid, tetanus toxoid, pertussis vaccine (children &lt;7 years old), Haemophilus influenzae type b conjugate, 23-valent pneumococcal polysaccharide, inactivated influenza vaccine, inactivated polio vaccine and live-attenuated measles-mumps-rubella vaccine are the currently recommended vaccines to be included in a vaccination program after BMT. For most of them, the best time to vaccinate, the number of vaccine doses and/or the duration of immunity after vaccination have not been established. Vaccination protocols vary greatly among BMT...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bone marrow transplantation; Vaccination; Autologous; Allogeneic; Toxoid; Polysaccharide.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100021

Immunological effects of donor lymphocyte infusion in patients with chronic myelogenous leukemia relapsing after bone marrow transplantation
Provedor de dados: 56
Autores: Castro,F.A.; Palma,P.V.B.; Morais,F.R.; Voltarelli,J.C.
Allogeneic bone marrow transplantation (alloBMT) is the only curative therapy for chronic myelogenous leukemia (CML). This success is explained by the delivery of high doses of antineoplastic agents followed by the rescue of marrow function and the induction of graft-versus-leukemia reaction mediated by allogeneic lymphocytes against host tumor cells. This reaction can also be induced by donor lymphocyte infusion (DLI) producing remission in most patients with CML who relapse after alloBMT. The immunological mechanisms involved in DLI therapy are poorly understood. We studied five CML patients in the chronic phase, who received DLI after relapsing from an HLA-identical BMT. Using flow cytometry we evaluated cellular activation and apoptosis, NK...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Chronic myelogenous leukemia; Donor lymphocyte infusion; Immune system; Bone marrow transplantation.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200006

Fungal infections in marrow transplant recipients under antifungal prophylaxis with fluconazole
Provedor de dados: 56
Autores: Oliveira,J.S.R.; Kerbauy,F.R.; Colombo,A.L.; Bahia,D.M.M.; Pinheiro,G.S.; Silva,M.R.R.; Ribeiro,M.S.S.; Raineri,G.; Kerbauy,J.
Fungal infection is one of the most important causes of morbidity and mortality in bone marrow transplant (BMT) recipients. The growing incidence of these infections is related to several factors including prolonged granulocytopenia, use of broad-spectrum antibiotics, conditioning regimens, and use of immunosuppression to avoid graft-versus-host disease (GvHD). In the present series, we report five cases of invasive mold infections documented among 64 BMT recipients undergoing fluconazole antifungal prophylaxis: 1) A strain of Scedosporium prolificans was isolated from a skin lesion that developed on day +72 after BMT in a chronic myeloid leukemic patient. 2) Invasive pulmonary aspergillosis (Aspergillus fumigatus) was diagnosed on day +29 in a patient...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bone marrow transplantation; Fungal infections; Fluconazole prophylaxis.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000700005