Consulta: subjectFacets:"Bothrops asper"
Registros recuperados: 5
Data/hora: 09/06/2024 02:17:55

Abscess secondary to facial snakebite
Provedor de dados: 79
Autores: QUIROGA,M.; AVILA-AGÜERO,M. L.; FAINGEZICHT,I.
In Costa Rica, approximately 700 snakebite cases occur each year, 5 to 10 of which result in death. At the Hospital Nacional de Niños (HNN), 6 to 10 cases are reported annually, more than half of these cases and nearly all deaths are result from Bothrops asper snakebite. This venomous snake, popularly known as the "terciopelo", most often attacks the lower or upper limbs and characteristically produces local tissue damage, which can be severe. The following is a report of the first case of a non-fatal and unusual facial bite caused by Bothrops asper in our country.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Snakebite; Abscess; Bothrops asper.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200009

Purification and partial characterization of phospholipases A2 from Bothrops asper (barba amarilla) snake venom from Chiriguaná (Cesar, Colombia)
Provedor de dados: 80
Autores: Ramírez-Avila,J.; Quevedo,B. E.; López,E.; Renjifo,J. M.
Components with phospholipase A2 activity were isolated by gel filtration and cationic exchange chromatography from the venom of Bothrops asper snakes from Chiriguaná, Colombia (9°22´N; 73°37´W). Five fractions were obtained by the gel filtration, and PLA2 activity was found in fraction 3 (F3). In the cationic exchange chromatography, F3 showed eight components with PLA2 activity. Six of these components appeared as one band in polyacrylamide gel electrophoresis (SDS-PAGE). Fractions II and VII exhibited an optimal activity at pH 9 and 52ºC. The optimum calcium concentration for fraction II was 48 mM and for fraction VII, 384 mM. Both fractions showed thermal stability. Fraction II was stable at pH values between 2.5 and 9, and fraction VII, between 2.5...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Phospholipase; Isoenzymes; Snake; Venom; Bothrops asper; Colombia.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992004000300005

Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect
Provedor de dados: 80
Autores: Dias,Renata Gonçalves; Sampaio,Sandra Coccuzzo; Sant’Anna,Morena Brazil; Cunha,Fernando Queiroz; Gutiérrez,José María; Lomonte,Bruno; Cury,Yara; Picolo,Gisele.
Abstract  Background  Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives. These are multi-mediated pathologies that cannot be effectively protected and/or treated. Therefore, the aim of this study was to establish a new model of acute arthritis, using a Lys49-PLA2 (Bothrops asper myotoxin II; MT-II) to induce articular inflammation.  Methods  The articular inflammation was induced by MT-II (10 μg/joint) injection into the left tibio-tarsal or femoral-tibial-patellar joints. Cellular influx was evaluated counting total and differential cells that migrated to the joint. The plasma extravasation was determined using Evans blue dye. The...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lys49-PLA2; Myotoxin II; Arthritis; Bothrops asper; Phospholipase.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100307

Efecto de plantas usadas etnomédicamente sobre la actividad hemorrágica y proteolítica inducida por Bothrops asper
Provedor de dados: 98
Autores: Badilla Baltodano,Beatriz; Chaves Mora,Fernando; Poveda Álvarez,Luis Jorge; Jiménez Castro,Sandra; Rodríguez Rodríguez,Gina.
Se evaluó la capacidad para neutralizar la acción hemorrágica y proteolítica causada por el veneno de la serpiente Bothrops asper de extractos acuosos de 5 plantas utilizadas etnomédicamente para tratar este problema. Este trabajo forma parte de un estudio de tamizaje farmacológico sobre las plantas usadas por los curanderos para tratar las mordeduras de serpientes. Se usaron extractos liofilizados de las hojas de Buddleja americana H.B.&amp; K. (Buddlejaceae), Mikania guaco Humb. &amp;amp; Bonpl. (Asteraceae), Piper darienense C.DC. in DC. (Piperaceae), Vernonia patens Kunth (GCI) (Asteraceae), y de la raíz de Echinacea purpurea (L.) Moench (Asteraceae) . Se usó el modelo de Kondo modificado para evaluar la actividad antihemorrágica y 2 métodos para...
Tipo: Journal article
Palavras-chave: Hemorragia; Proteólisis; Plantas; Extractos acuosos; Bothrops asper; Buddleja americana; Mikania guaco; Piper darienense; Vernonia patens; Echinacea purpurea.
Ano: 2006
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962006000100005

Isolation and characterization of a serine proteinase with thrombin-like activity from the venom of the snake Bothrops asper
Provedor de dados: 56
Autores: Pérez,A.V; Rucavado,A; Sanz,L; Calvete,J.J; Gutiérrez,J.M.
A serine proteinase with thrombin-like activity was isolated from the venom of the Central American pit viper Bothrops asper. Isolation was performed by a combination of affinity chromatography on aminobenzamidine-Sepharose and ion-exchange chromatography on DEAE-Sepharose. The enzyme accounts for approximately 0.13% of the venom dry weight and has a molecular mass of 32 kDa as determined by SDS-PAGE, and of 27 kDa as determined by MALDI-TOF mass spectrometry. Its partial amino acid sequence shows high identity with snake venom serine proteinases and a complete identity with a cDNA clone previously sequenced from this species. The N-terminal sequence of the enzyme is VIGGDECNINEHRSLVVLFXSSGFL CAGTLVQDEWVLTAANCDSKNFQ. The enzyme induces clotting of plasma...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Snake venom; Bothrops asper; Serine proteinase; Thrombin-like serine proteinase; Defibrin(ogen)ation.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000100003