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Differences in the replicative capacities of clinical isolates of dengue virus in C6/36 cells and in urban populations of Aedes aegypti from Colombia, South America
Provedor de dados: 55
Autores: Quintero-Gil,Diana Carolina; Uribe-Yepes,Alexander; Ospina,Marta; Díaz,Francisco Javier; Martinez-Gutierrez,Marlen.
ABSTRACT Dengue, the most prevalent arboviral disease worldwide, is caused by any of the four dengue virus (DENV) serotypes that co-circulate constantly in hyperendemic areas such as Medellin (Colombia), and these serotypes are transmitted by mosquitoes of the genus Aedes. In this study, we evaluated the replicative capacity of strains isolated in Medellin between 2003 and 2007 in C6/36 cells and in colonies of Aedes aegypti collected during 2010-2011 from high or low-incidence areas within the same city. The phylogenetic analysis grouped isolates according to the predominant genotypes found in the Americas, and the in vitro characterization showed differences in the morphological changes induced by the isolates of each of the isolated serotypes compared...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Dengue; Viral replication; Vector competence; Aedes aegypti; C6/36 cells; Colombia.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000400257