Consulta: subjectFacets:"Cancer vaccine"
Registros recuperados: 2
Data/hora: 08/06/2024 14:05:26

Personal history of infections and immunotherapy: unexpected links and possible therapeutic opportunities
Provedor de dados: 5
Autores: Jacqueline, Camille; Bonnefoy, Nathalie; Charriere, Guillaume; Thomas, Frederic; Roche, Benjamin.
The recent breakthroughs in the understanding of tumor immune biology have given rise to a new generation of immunotherapies, harnessing the immune system to eliminate tumors. As the typology and frequency of encountered infections are susceptible to shape the immune system, it could also impact the efficiency of immunotherapy. In this review, we report evidences for an indirect link between personal history of infection and different strategies of immunotherapy. In the current context of interest rise for personalized medicine, we discuss the potential medical applications of considering personal history of infection to design immunotherapeutic strategies.
Tipo: Text
Palavras-chave: Immunotherapy; Infections; Personalized medicine; Cancer vaccine; Immune checkpoints; Adoptive cell transfer.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00437/54865/57788.pdf

Live bacterial vaccine vectors: An overview
Provedor de dados: 58
Autores: Silva,Adilson José da; Zangirolami,Teresa Cristina; Novo-Mansur,Maria Teresa Marques; Giordano,Roberto de Campos; Martins,Elizabeth Angélica Leme.
Genetically attenuated microorganisms, pathogens, and some commensal bacteria can be engineered to deliver recombinant heterologous antigens to stimulate the host immune system, while still offering good levels of safety. A key feature of these live vectors is their capacity to stimulate mucosal as well as humoral and/or cellular systemic immunity. This enables the use of different forms of vaccination to prevent pathogen colonization of mucosal tissues, the front door for many infectious agents. Furthermore, delivery of DNA vaccines and immune system stimulatory molecules, such as cytokines, can be achieved using these special carriers, whose adjuvant properties and, sometimes, invasive capacities enhance the immune response. More recently, the unique...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bacterial vector; Vaccine delivery system; DNA vaccine; Cancer vaccine; Antigen presentation.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400001