Consulta: subjectFacets:"Cellular alterations"
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Data/hora: 05/06/2024 09:59:43

Genotoxicity of titanium dioxide nanoparticles and triggering of defense mechanisms in Allium cepa
Provedor de dados: Genetics and Molecular Biology
Autores: Santos Filho,Ronaldo dos; Vicari,Taynah; Santos,Samuel A.; Felisbino,Karoline; Mattoso,Ney; Sant’Anna-Santos,Bruno Francisco; Cestari,Marta Margarete; Leme,Daniela Morais.
Abstract Titanium dioxide nanoparticles (TiO2NPs) are widely used and may impact the environment. Thus, this study used a high concentration of TiO2NP (1000 mg/L) to verify the defense mechanisms triggered by a plant system – an indicator of toxicity. Furthermore, this study aimed at completely characterizing TiO2NP suspensions to elucidate their toxic behavior. TiO2NPs were taken up by meristematic cells of Allium cepa, leading to slight inhibition of seed germination and root growth. However, severe cellular and DNA damages were observed in a concentration-dependent manner (10, 100, and 1000 mg/L). For this reason, we used the highest tested concentration (1000 mg/L) to verify if the plant cells developed defense mechanisms against the TiO2NPs and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chromosomal aberrations; Micronuclei; Nucleolar alterations; Cellular alterations; Nanoparticle phase-change.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000300425