Consulta: subjectFacets:"Cerebellum"
Registros recuperados: 8
Data/hora: 07/06/2024 15:58:21

Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
Provedor de dados: 77
Autores: Kosif,Rengin; Sahin,Bünyamin; Gürel,Safiye.
Cerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimulant related to vision, how cerebellum is adopted under this circumstance? In order to explore this, 27 male and 16 female volunteers with bilateral congenital blindness were compared with 35 male and 33 female healthy volunteers in this study. MR images of cross-sectional sequential cerebellum of volunteers with 1.5 mm thickness were realized in coronal plane. The surface area of apparent cerebellum seen in cross-sections was calculated by using Onis (Ver. 2.1)...
Tipo: Journal article
Palavras-chave: Bilateral congenital blindness; Cerebellum; Volume.
Ano: 2013
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100039

Morphometric Evidences for Regional Variation in Potential of Neural Plasticity
Provedor de dados: 77
Autores: Fazeli,Seyyed Amirhossein; Davarian,Ali; Behnampour,Naser; Golalipour,Mohammad Jafar.
The neural plasticity showing the ability of nervous system to change its structure and function is a well-documented fact. However regional variation within a CNS structure to undergo plastic changes has been shown by limited studies. Along medial-lateral sequences of parasagittal sections, the molecular layer thickness of primary fissure borderlands in rat cerebellar left hemisphere was studied to assess the regional difference in plasticibility. Despite the homogeneity of cerebellar histology, this study showed that there is a significant interlobular difference between ML thicknesses of Prf borderlands. In addition, it revealed that the thickness alters in a significant trend within each borderland. The quantitative heterogeneity of cerebellar...
Tipo: Journal article
Palavras-chave: Plasticibility; Molecular layer; Primary fissure; Cerebellum; Rat.
Ano: 2006
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000300010

Cerebellar Vermis: Topography and Variations
Provedor de dados: 77
Autores: Bispo,Rodrigo Freitas Monte; Ramalho,Antonio José Casado; Gusmão,Luiz Carlos Buarque de; Cavalcante,Amundson Portela  de Holanda; Rocha,Amauri Clemente da; Sousa-Rodrigues,Célio Fernando de.
The vermis is described as the unpaired, median portion of the cerebellum to which the hemispheres are attached. Both the vermis and the hemispheres are formed by folia that, grouped together, are called lobules. The material analyzed consisted of a sample made up of 43 adult male cerebella fixed in 10% formaldehyde and sliced medially. The lingula was attached to the superior medullary velum in 100% (43) of the cerebella, varying only in size. In 80% (32) of the cerebella, the central lobe contained one folium; 7.5% (3) had two folia with the first larger than the second; 10% (4) had two folia with the second larger than the first; and 2.5% (1) had two folia of equal size. In 5% (2) of the cerebella, the folium of the vermis emerged from the declive; in...
Tipo: Journal article
Palavras-chave: Cerebellum; Vermis; Variation.
Ano: 2010
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000200018

Effect of Gestational Diabetes on Neuronal Cells in Rat Cerebellum in Early Postnatal Life
Provedor de dados: 77
Autores: Razi,Elahe Mirarab; Ghafari,Soraya; Hojati,Vida; Golalipour,Mohammad Jafar.
Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental study, 10 dams randomly allocated into control and diabetic groups on day 1 of gestation. Five dams in diabetic group were administered 40 mg/kg/BW (intraperitoneally) of streptozotocin and control animals received normal saline. Six offspring of each gestational diabetes mellitus and controls were randomly selected at day 7 of postnatal life. Offspring were sacrificed and coronal sections were taken from the cerebellum and stained with cresyl violet. The number of Purkinje and granular cells and thickness...
Tipo: Journal article
Palavras-chave: Gestational diabetes; Cerebellum; Purkinje cell; Granular cell; Rat.
Ano: 2014
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200006

Optimized Exon-Exon Junction Library and its Application on Rodents' Brain Transcriptome Analysis
Provedor de dados: 52
Autores: Dou,Tong-Hai; Gao,Yuan; Chen,Cheng-Wen; Xu,Min-Jie; Fu,Mao-Bin; Zhang,Liang; Zhou,Yan.
ABSTRACT  Background: Alternative splicing (AS), which plays an important role in gene expression and functional regulation, has been analyzed on genome-scale by various bioinformatic approaches based on RNA-seq data. Compared with the huge number of studies on mouse, the AS researches approaching the rat, whose genome is intermedia between mouse and human, were still limited. To enrich the knowledge on AS events in rodents' brain, we perfomed a comprehensive analysis on four transcriptome libraries (mouse cerebrum, mouse cerebellum, rat cerebrum, and rat cerebellum), recruiting high-throughput sequencing technology. An optimized exon-exon junction library approach was introduced to adapt the longer RNA-seq reads and to improve mapping efficiency....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: RNA-seq; Exon-exon junction; Alternative splicing; Cerebrum; Cerebellum.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100400

Low-dose thioperamide injected into the cerebellar vermis of mice immediately after exposure to the elevated plus-maze impairs their avoidance behavior on re-exposure to the apparatus
Provedor de dados: 56
Autores: Costa Neto,J.; Serafim,K.R.; Gianlorenço,A.C.L.; Mattioli,R.
The present study investigated the effect of thioperamide (THIO), an H3 histaminergic receptor antagonist, microinjected into the cerebellar vermis on emotional memory consolidation in male Swiss albino mice re-exposed to the elevated plus-maze (EPM). We implanted a guide cannula into the cerebellar vermis using stereotactic surgery. On the third day after surgery, we performed behavioral tests for two consecutive days. On the first day (exposure), the mice (n=10/group) were exposed to the EPM and received THIO (0.06, 0.3, or 1.5 ng/0.1 µL) immediately after the end of the session. Twenty-four hours later, the mice were re-exposed to the EPM under the same experimental conditions, but without drug injection. A reduction in the exploration of the open arms...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Histaminergic system; Cerebellum; H3; Emotional memory; Memory consolidation; Elevated plus-maze.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100943

The extracellular matrix provides directional cues for neuronal migration during cerebellar development
Provedor de dados: 56
Autores: Porcionatto,M.A.
Normal central nervous system development relies on accurate intrinsic cellular programs as well as on extrinsic informative cues provided by extracellular molecules. Migration of neuronal progenitors from defined proliferative zones to their final location is a key event during embryonic and postnatal development. Extracellular matrix components play important roles in these processes, and interactions between neurons and extracellular matrix are fundamental for the normal development of the central nervous system. Guidance cues are provided by extracellular factors that orient neuronal migration. During cerebellar development, the extracellular matrix molecules laminin and fibronectin give support to neuronal precursor migration, while other molecules...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Extracellular matrix; Central nervous system; Cerebellum; Neuron; Migration.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000300001

Transient outward potassium current and Ca2+ homeostasis in the heart: beyond the action potential
Provedor de dados: 56
Autores: Bassani,R.A.
Normal central nervous system development relies on accurate intrinsic cellular programs as well as on extrinsic informative cues provided by extracellular molecules. Migration of neuronal progenitors from defined proliferative zones to their final location is a key event during embryonic and postnatal development. Extracellular matrix components play important roles in these processes, and interactions between neurons and extracellular matrix are fundamental for the normal development of the central nervous system. Guidance cues are provided by extracellular factors that orient neuronal migration. During cerebellar development, the extracellular matrix molecules laminin and fibronectin give support to neuronal precursor migration, while other molecules...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Extracellular matrix; Central nervous system; Cerebellum; Neuron; Migration.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000300010