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Distribution of the a2, a3, and a5 nicotinic acetylcholine receptor subunits in the chick brain
Provedor de dados: 56
Autores: Torrão,A.S.; Lindstrom,J.M.; Britto,L.R.G.
Nicotinic acetylcholine receptors (nAChRs) are ionotropic receptors comprised of &lt;FONT FACE="Symbol"&gt;a&lt;/font&gt; and ß subunits. These receptors are widely distributed in the central nervous system, and previous studies have revealed specific patterns of localization for some nAChR subunits in the vertebrate brain. In the present study we used immunohistochemical methods and monoclonal antibodies to localize the &lt;FONT FACE="Symbol"&gt;a&lt;/font&gt;2, &lt;FONT FACE="Symbol"&gt;a&lt;/font&gt;3, and &lt;FONT FACE="Symbol"&gt;a&lt;/font&gt;5 nAChR subunits in the chick mesencephalon and diencephalon. We observed a differential distribution of these three subunits in the chick brain, and showed that the somata and neuropil of many central...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cholinergic system; Neurotransmitters; Receptors; Receptor subunits.
Ano: 1997
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000011