Consulta: subjectFacets:"Cord blood"
Registros recuperados: 2
Data/hora: 29/05/2024 03:33:47

Human erythroid progenitors from adult bone marrow and cord blood in optimized liquid culture systems respectively maintained adult and neonatal characteristics of globin gene expression
Provedor de dados: Biological Research
Autores: ZHANG,XIN; MA,YAN-NI; ZHANG,JUN-WU.
In vitro suspension culture procedures for erythroid progenitor cells make it possible for us to obtain large cultures of erythrocyte populations for the investigation of globin gene switching. In this study we aimed to establish optimized culture systems for neonatal and adult erythroblasts and to explore the globin expression patterns in these culture systems. To culture CD34+ cells purified from human umbilical cord blood (CB) and adult bone marrow (BM), we respectively replaced the fetal bovine serum (FBS) with human cord serum and human adult serum. These CD34+ cells were then induced to erythroid differentiation. All the globin mRNA (including á-, &amp;#958;-, &amp;#946;-, &amp;#947;-and &amp;#949;-globin), the hemoglobin (Hb)-producing erythroid...
Tipo: Journal article
Palavras-chave: Adult bone marrow; Cord blood; Erythroid progenitor; Globins; Liquid culture.
Ano: 2007
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000100005

Atherogenic lipid profile of Brazilian near-term newborns
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Pardo,I.M.C.G.; Geloneze,B.; Tambascia,M.A.; Barros-Filho,A.A.
Cardiovascular disease is the primary cause of death in Brazil. Recent studies have shown that low birth weight and preterm birth are linked to a higher prevalence of cardiovascular disease. The aim of the present study was to compare the levels of lipids and apolipoproteins and atherogenic indexes between term and near-term newborn infants. A sample of umbilical cord blood was obtained from 135 newborns (66 males) divided into two groups: 25 near-term neonates (35-36.6 weeks of gestational age) and 110 term neonates (37-42 weeks of gestational age). The total cholesterol concentrations were higher in the near-term neonates than in the term group (94.04 ± 8.02 vs 70.42 ± 1.63 mg/dl, P &lt; 0.01), due to an increase in the LDL-cholesterol fraction in the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lipids; Apolipoproteins; Cholesterol; Cord blood; Cardiovascular disease; Newborns.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000500013