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Diagnosis of histoplasmosis
Provedor de dados: Brazilian Journal of Microbiology
Autores: Guimarães,Allan Jefferson; Nosanchuk,Joshua D.; Zancopé-Oliveira,Rosely Maria.
Endemic mycoses can be challenging to diagnose and accurate interpretation of laboratory data is important to ensure the most appropriate treatment for the patients. Although the definitive diagnosis of histoplasmosis (HP), one of the most frequent endemic mycoses in the world, is achieved by direct diagnosis performed by micro and/or macroscopic observation of Histoplasma capsulatum (H. capsulatum), serologic evidence of this fungal infection is important since the isolation of the etiologic agents is time-consuming and insensitive. A variety of immunoassays have been used to detect specific antibodies to H. capsulatum. The most applied technique for antibody detection is immunodiffusion with sensitivity between 70 to 100 % and specificity of 100%,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Diagnostic tests; Culture based methods; Molecular methods; Serology.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000100001