Consulta: subjectFacets:"Cynara scolymus L. Asteraceae"
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Data/hora: 02/06/2024 10:38:06

In vitro investigations of Cynara scolymus L. extract on cell physiology of HepG2 liver cells
Provedor de dados: 60
Autores: Löhr,Gesine; Deters,Alexandra; Hensel,Andreas.
The objective of this study was the investigation of a potential influence of artichoke leaf extract (ALE) on the cell physiology and gene expression of phase I/II enzymes of human liver cells HepG2 and investigation on potential cell protective effects against ethanol-induced cell toxicity against HepG2 cells. Cell biological assays under in vitro conditions using HepG2 liver cells and investigation of mitochondrial activity (MTT test), proliferation assay (BrdU incorporation ELISA), LDH as toxicity marker, gene expression analysis by RT-PCR and enzyme activity of glutationtransferase. Artichocke extract, containing 27% caffeoylquinic acids and 7% flavonoids induced mitochondrial activity, proliferation and total protein content under in vitro conditions...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cynara scolymus L. Asteraceae; Artichoke; Liver cells; Cell proliferation; Gene expression.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200003