Consulta: subjectFacets:"Echis coloratus"
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Antitumor and biochemical effects of Echis coloratus crude venom on Ehrlich ascites carcinoma cells in vivo
Provedor de dados: 79
Autores: MADY,E. A.
The search for snake venom antitumor efficacy has attracted the interest of scientists since the beginning of last century. Snake venom possesses a wide spectrum of biological activities. In this study, we evaluated the effect of Echis coloratus crude venom on the evolution of Ehrlich ascites carcinoma cells (EAC). Normal and EAC-bearing mice were treated with 0.2 mg/kg body weight of crude venom. Crude venom was seen to suppress tumor growth by significantly decreasing EAC cell count and cell viability (p&lt;0.01). There was also a significant increase in survival time of the venom-treated tumor-bearing mice (52.3%, p&lt;0.05) in comparison to the non-treated tumor-bearing counterparts. The study of venom effect and/or tumor inoculation on some important...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Snake venom; Echis coloratus; Ehrlich ascites carcinoma; Tumor growth; Biochemistry.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200008