Consulta: subjectFacets:"Fungal infections"
Registros recuperados: 12
Data/hora: 10/06/2024 13:42:59

Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report
Provedor de dados: Journal of Venomous Animals and Toxins Including Tropical Diseases
Autores: Dantas,Kátia Cristina; Freitas,Roseli Santos de; Garcia,Roberta Scholz Pinto; Silva,Marcos Vinícius da; Muricy,Edna Cleide Mendes; Kohara,Valdelene Sayuri; Vicentini,Adriana Pardini.
This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum andCryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Immunocompetent individuals; Nested PCR; Immunoblotting; Fungal infections; Blood fluid.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200507

Monetary costs and hospital burden associated with the management of invasive fungal infections in Mexico: a multicenter study
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Corzo-León,Dora Edith; Perales-Martínez,Diana; Martin-Onraet,Alexandra; Rivera-Martínez,Norma; Camacho-Ortiz,Adrian; Villanueva-Lozano,Hiram.
ABSTRACT  Background: Invasive fungal infections (IFIs) affect &gt;1.5 million people per year. Nevertheless, IFIs are usually neglected and underdiagnosed. IFIs should be considered as a public-health problem and major actions should be taken to tackle them and their associated costs. Aim To report the incidence of IFIs in four Mexican hospitals, to describe the economic cost associated with IFIs therapy and the impact of adverse events such as acute kidney injury (AKI), liver damage (LD), and ICU stay.  Methods: This was a retrospective, transversal study carried-out in four Mexican hospitals. All IFIs occurring during 2016 were included. Incidence rates and estimation of antifungal therapy's expenditure for one year were calculated. Adjustments for...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fungal infections; Antifungal therapy; Cost; Acute kidney injury; Incidence rate; Mexico.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500360

Hospital-associated funguria: analysis of risk factors, clinical presentation and outcome
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Carvalho,Mauricio; Guimarães,César Maistro; Mayer Júnior,José Ronaldo; Bordignon,Gisele P. Fernandes; Queiroz-Telles,Flávio.
Fungal urinary tract infections are an increasing problem in hospitalized patients. Funguria may be a result of contamination of the urine specimen, colonization of the urinary tract, or may be indicative of true invasive infection. In this study, we report the risk factors, clinical features, treatments and outcome in a group of 68 hospitalized patients (adults and children) with fungal isolates recovered from 103 urinary samples. Underlying medical conditions were present in most patients. In the pediatric group, urinary tract abnormalities (86%) and prematurity (19%) accounted for the majority of the cases. Diabetes mellitus (28%), nephrolithiasis, and benign prostatic hyperplasia were the most common diseases in adults. Indwelling urethral catheters...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Funguria; Candiduria; Fungal infections.
Ano: 2001
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000600004

A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Carlesse,Fabianne; Daudt,Liane Esteves; Seber,Adriana; Dutra,Álvaro Pimenta; Melo,Analy Salles de Azevedo; Simões,Belinda; Macedo,Carla Renata Donato; Bonfim,Carmem; Benites,Eliana; Gregianin,Lauro; Batista,Marjorie Vieira; Abramczyk,Marcelo; Tostes,Vivian; Lederman,Henrique Manoel; Lee,Maria Lúcia de Martino; Loggetto,Sandra; Castro Junior,Cláudio Galvão de; Colombo,Arnaldo Lopes.
ABSTRACT In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fungal infections; Children; Cancer.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000600395

Fusarium spp infections in a pediatric burn unit: nine years of experience
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Rosanova,María Teresa; Brizuela,Martín; Villasboas,Mabel; Guarracino,Fabian; Alvarez,Veronica; Santos,Patricia; Finquelievich,Jorge.
Abstract  Introduction Fusarium spp are ubiquitous fungi recognized as opportunistic agents of human infections, and can produce severe infections in burn patients. The literature on Fusarium spp infections in pediatric burn patients is scarce.  Objectives To describe the clinical and epidemiological features as well as outcome of Fusarium spp infections in pediatric burn patients.  Patients and methods Retrospective, descriptive study of Fusarium spp infections in a specialized intensive care burn unit.  Results In 15 patients Fusarium spp infections were diagnosed. Median age was 48 months. Direct fire injury was observed in ten patients. The median affected burn surface area was 45%. Twelve patients had a full thickness burn. Fourteen patients had a...
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Burn; Fusarium spp; Fungal infections.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000400389

Septic arthritis as the first sign of Candida tropicalis fungaemia in an acute lymphoid leukemia patient
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Vicari,Perla; Pinheiro,Ronald Feitosa; Chauffaille,Maria de Lourdes Lopes Ferrari; Yamamoto,Mihoko; Figueiredo,Maria Stella.
Fungal infections caused by Candida species have increased in incidence during the past two decades in England, North America and Europe. Candidal arthritis is rare in patients who are not intravenous drug users or are who not using a prostheses. We report the case of a 24-year-old man with acute lymphoid leukemia, who developed Candida tropicalis arthritis during an aplastic period after chemotherapy. This is the eighth case described in the literature of C. tropicalis causing arthritis without intra-articular inoculation. We call attention to an unusual first sign of fungal infection: septic arthritis without intra-articular inoculation. However, this case differs from the other seven, since despite therapy a fast and lethal evolution was observed. We...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Septic arthritis; Candida tropicalis; Fungal infections; Candida tropicalis arthritis; Systemic candidiasis.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600012

Cerebral aspergillosis presenting as a mass lesion
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Azarpira,Negar; Esfandiari,Majid; Bagheri,Mohamad Hadi; Rakei,Sed; Salari,Soheila.
Fungal infections of the central nervous system (CNS) are almost always a surprising finding. Their presentation is usually subtle, often without any diagnostic characteristics, and they are frequently mistaken for pyogenic abscesses, or brain tumors. Aspergillosis of the central nervous system is an uncommon infection, mainly occurring in immunocompromised patients. It may present in several forms, including meningitis, mycotic aneurysms, infarcts and a tumoral form. We report an intracranial granuloma due to Aspergillus fumigatus involving the anterior cranial fossa and the frontal lobe. The clinical symptoms began one year before admission. Final diagnosis was made after craniotomy. The patient was treated with an extensive excision of the cerebral mass...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Granulomatous inflammation; Aspergillus fumigatus; Fungal infections.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400019

Fungal infections in marrow transplant recipients under antifungal prophylaxis with fluconazole
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Oliveira,J.S.R.; Kerbauy,F.R.; Colombo,A.L.; Bahia,D.M.M.; Pinheiro,G.S.; Silva,M.R.R.; Ribeiro,M.S.S.; Raineri,G.; Kerbauy,J.
Fungal infection is one of the most important causes of morbidity and mortality in bone marrow transplant (BMT) recipients. The growing incidence of these infections is related to several factors including prolonged granulocytopenia, use of broad-spectrum antibiotics, conditioning regimens, and use of immunosuppression to avoid graft-versus-host disease (GvHD). In the present series, we report five cases of invasive mold infections documented among 64 BMT recipients undergoing fluconazole antifungal prophylaxis: 1) A strain of Scedosporium prolificans was isolated from a skin lesion that developed on day +72 after BMT in a chronic myeloid leukemic patient. 2) Invasive pulmonary aspergillosis (Aspergillus fumigatus) was diagnosed on day +29 in a patient...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bone marrow transplantation; Fungal infections; Fluconazole prophylaxis.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000700005

Clinical significance of the isolation of Candidaspecies from hospitalized patients
Provedor de dados: Brazilian Journal of Microbiology
Autores: Magalhães,Yankee C.; Bomfim,Maria Rosa Q.; Melônio,Luciane C.; Ribeiro,Patrícia C.S.; Cosme,Lécia M.; Rhoden,Cristianne R.; Marques,Sirlei G.
In this study, we isolated and phenotypically identified 108 yeast strains from various clinical specimens collected from 100 hospitalized patients at three tertiary hospitals in São Luís-Maranhão, Brazil, from July to December 2010. The isolates were analyzed for their susceptibility to four of the most widely used antifungal agents in the surveyed hospitals, amphotericin B, fluconazole, 5-flucytosine and voriconazole. The species identified were Candida albicans (41.4%), Candida tropicalis (30.1%), C. glabrata (7.4%), Candida parapsilosis(5.5%), Candida krusei (4.6%), Cryptococcus neoformans (4.6%), Trichosporonspp. (3.7%), Candida norvegensis (0.9%), Rhodotorula glutinis (0.9%) and Pichia farinosa (0.9%). A higher isolation rate was observed in the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fungal infections; Susceptibility profile; Nosocomial infections.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100117

Invasive Trichosporon cutaneum infection in an infant with wilms' tumor
Provedor de dados: Brazilian Journal of Microbiology
Autores: Carvalho,Ana Maria Rabelo de; Melo,Luciana Resende Bandeira de; Moraes,Vera Lúcia; Neves,Rejane Pereira.
Fungal infections are increasingly being reported in immuno-compromised patients. In this study we report a case of systemic Trichosporon cutaneum infection in an infant with Wilms' tumor. This is the first time that an invasive infection for T. cutaneum has been reported in a Wilms' tumor patient.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fungal infections; Trichosporon cutaneum; An infant; Diagnosis; Wilms' tumor.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000100014

A 7-year survey of superficial and cutaneous mycoses in a public hospital in Natal, Northeast Brazil
Provedor de dados: Brazilian Journal of Microbiology
Autores: Calado,Nicácia Barbosa; Sousa Júnior,Francisco Canindé de; Diniz,Mariana Guimarães; Fernandes,Ana Cristina Santos; Cardoso,Fernando José Ramos; Zaror,Luiz Conrado; Ferreira,Maria Ângela Fernandes; Milan,Eveline Pipolo.
In the present study, we determined the frequency of superficial and cutaneous mycoses and their etiologic agents during a 7-year period (2002-2008) in Natal, Brazil. A total of 1,717 specimens of skin, nail, and hair were collected from 1,382 patients with suspected mycoses lesions and were then subjected to direct microscopy and culture.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cutaneous mycoses; Dermatophytes; Fungal infections; Yeasts; Superficial mycoses.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400008

Design, preparation and in vitro characterizations of fluconazole loaded nanostructured lipid carriers
Provedor de dados: Brazilian Journal of Pharmaceutical Sciences
Autores: Fernandes,Amanda Velinna; Pydi,Chinna Raja; Verma,Ruchi; Jose,Jobin; Kumar,Lalit.
Present study was aimed to prepare and characterize fluconazole loaded nanostructured lipid carriers (FLZ-NLCs) for the treatment of fungal infections. Fungal infections are tremendously widespread and are the often faced dermatological condition worldwide. FLZ-NLCs was prepared by ultrasonication emulsion technique using stearic acid (SA) as solid lipid, castor oil as liquid lipid and tween 20 as a surfactant. The mean diameter of optimized FLZ-NLCs were found to be 359.15 ± 9.83 nm. The drug content and entrapment efficiency of NLCs was found to be 102.97 ± 7.45% and 87 ± 0.59%, respectively. In vitro drug release studies of FLZ-NLCs showed 37.34 ± 2.08% drug release over a period of 72 h. The above studies confirmed the prepared FLZ-NLCs may be useful...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fluconazole; NLCs; Nanostructured lipid carriers; Fungal infections; Full factorial design; Design of experiment.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100524