Consulta: subjectFacets:"Glycyrrhizin"
Registros recuperados: 2
Data/hora: 17/06/2024 15:09:03

Combination therapy of orally administered glycyrrhizin and UVB improved active-stage generalized vitiligo
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Mou,K.H.; Han,D.; Liu,W.L.; Li,P.
Glycyrrhizin has been used clinically for several years due to its beneficial effect on immunoglobulin E (IgE)-induced allergic diseases, alopecia areata and psoriasis. In this study, glycyrrhizin, ultraviolet B light (UVB) or a combination of both were used to treat active-stage generalized vitiligo. One hundred and forty-four patients between the ages of 3 and 48 years were divided into three groups: group A received oral compound glycyrrhizin (OCG); group B received UVB applications twice weekly, and group C received OCG+UVB. Follow-ups were performed at 2, 4, and 6 months after the treatment was initiated. The Vitiligo Area Scoring Index (VASI) and the Vitiligo Disease Activity (VIDA) instrument were used to assess the affected body surface, at each...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Glycyrrhizin; UVB; Generalized vitiligo; Disease stage; Active stage.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000800605

Glycyrrhizin attenuates endotoxin- induced acute liver injury after partial hepatectomy in rats
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Tang,B.; Qiao,H.; Meng,F.; Sun,X.
Massive hepatectomy associated with infection induces liver dysfunction, or even multiple organ failure and death. Glycyrrhizin has been shown to exhibit anti-oxidant and anti-inflammatory activities. The aim of the present study was to investigate whether glycyrrhizin could attenuate endotoxin-induced acute liver injury after partial hepatectomy. Male Wistar rats (6 to 8 weeks old, weighing 200-250 g) were randomly assigned to three groups of 24 rats each: sham, saline and glycyrrhizin. Rats were injected intravenously with lipopolysaccharide (LPS) 24 h after 70% hepatectomy. Glycyrrhizin, pre-administered three times with 24 h intervals 48 h before hepatectomy, prolonged the survival of rats submitted to partial hepatectomy and LPS injection, compared...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Glycyrrhizin; Lipopolysaccharide; Hepatectomy; Inflammatory cytokine; Apoptosis; Endotoxemia.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001200007