Consulta: subjectFacets:"Guinea pig"
Registros recuperados: 9
Data/hora: 06/06/2024 07:27:08

MORPHOLOGICAL ALTERATIONS IN THE MASSETER MUSCLE INDUCED BY UNILATERAL EXTRACTION OF THE UPPER MOLARS IN GUINEA PIGS (Cavia porcellus)
Provedor de dados: 77
Autores: Mardegan Issa,João Paulo; Mizusaki Iyomasa,Mamie; Ioshie Mizusaki,Cristina; Watanabe,Ii-sei; Mandarim de Lacerda,Carlos Alberto.
The objective of the present study was to analyze morphological aspects of the structures of the stomatognathic system and their relationship with malocclusion. For this purpose, we determined the morphological alterations that occur in the masseter muscle of guinea pigs (Cavia porcellus) after the induction of malocclusion by extraction of the left upper molars. Animals were divided into two groups (malocclusion and control group) and submitted to macroscopic, biometric and light microscopic analyses. The results showed a reduction in the width of the masseter muscle mainly in left side in the malocclusion group 60 days after unilateral extraction. Microscopically, round and polygonal muscle fibers of several diameters were observed, and altered muscle...
Tipo: Journal article
Palavras-chave: Masseter muscle; Morphology; Light microscopy; Muscle fibers; Guinea pig.
Ano: 2004
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022004000300009

Comparison of Enterotoxicity between Autumn Crocus (Colchicum autumnale L.) and Colchicine in the Guinea Pig and Mouse : Enterotoxicity in the Guinea Pig Differs from That in the Mouse
Provedor de dados: 19
Autores: YAMADA, Manabu; KOBAYASHI, Yoshiyasu; FURUOKA, Hidefumi; MATSUI, Takane; 古林, 与志安; 古岡, 秀文.
Autumn crocus poisoning of cattle is characterized by severe diarrhea caused by alkaloid colchicine. Previously, we examined pathologically this poisoning in cattle and reported that enterotoxic lesions were closely associated with apoptosis. To examine enterotoxicity of autumn crocus more precisely, a reproductive study was performed using guinea pigs and mice, and pathological findings associated with autumn crocus poisoning were compared with those of colchicine. Each group of guinea pigs given the bulb of autumn crocus or colchicine exhibited severe diarrhea. Histopathological findings in intoxicated guinea pigs were entirely consistent with those in the autumn crocus-poisoned cattle. In contrast, each group of mice administered with the bulb or...
Palavras-chave: Apoptosis; Autumn crocus (Colchicum autumnale L.); Colchicine; Guinea pig; Mouse.
Ano: 2000
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4170

Molecular diversity among domestic guinea-pigs (Cavia porcellus) and their close phylogenetic relationship with the Andean wild species Cavia tschudii
Provedor de dados: 97
Autores: SPOTORNO,ÁNGEL E; VALLADARES,JOHN P; MARÍN,JUAN C; ZEBALLOS,HORACIO.
To investigate the origin and diversity of domestic guinea-pigs Cavia porcellus (Linnaeus, 1758; Rodentia, Caviidae), we sequenced the mitochondrial cytochrome b gene of 12 domestic and 10 wild specimens from six species, including the two presumed as ancestral to the domestic one: Cavia tschudii and Cavia aperea. All maximum parsimony and maximum likelihood analyses grouped C. porcellus with C. tschudii (mean K2P distance = 3.2 %); best trees had 609 steps (CI = 0.796; Bremer support Index (SI) = 28), and a _Ln = 4419.52, with 100 % and 97 % bootstrap support respectively. This clade, supported by three substitutions and 96 % bootstrap, is also obtained in the cladistic analysis of corresponding amino acids. When the C. aperea node was forced to join C....
Tipo: Journal article
Palavras-chave: Andes; Cavidae; Cytochrome b; Domestication; Guinea pig; Molecular phylogeny.
Ano: 2004
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2004000200004

Helminths of the guinea pig, Cavia porcellus (Linnaeus), in Brazil
Provedor de dados: 104
Autores: Pinto,Roberto Magalhães; Gomes,Delir Corrêa; Muniz-Pereira,Luís C.; Noronha,Dely.
Worm burdens were evaluated and compared in two groups of the guinea pig, Cavia poreellus (Linnaeus, 1758): animals of the first group were conventionally maintained in an institutional animal house and those of the second group were openly kept in pet shops in Brazil. Animals from both sources were infected only with the nematode Paraspidodera uncinata (Rudolphi, 1819) Travassos, 1914 (10% of prevalence in guinea pigs from lhe institutional facility and 40% in those animals from the pet shop). Other helminth samples recovered from Brazilian guinea pigs during 52 years and that are deposited in the Helminthological Collection of the Oswaldo Cruz Institute (CHIOC) were also analyzed. Paraspidodera uncinata and the cestode Monoecocestus parcitesticulatus...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Helminths; Paraspidodera uncinata; Monoecocestus parcitesticulatus; Cavia poreellus; Guinea pig; Brazil.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-81752002000500020

In vitro evaluation of Clostridium septicum alpha toxoid
Provedor de dados: 45
Autores: Salvarani,F.M.; Lobato,Z.I.P.; Assis,R.A.; Lima,C.G.R.D.; Silva,R.O.S.; Pires,P.S.; Lobato,F.C.F.
Aiming to investigate in vitro alternatives, a test for neutralizing antibody detection using cell culture was developed. This test was more sensitive than previous animal models, allowing for detection of substantially lower alpha toxin and anti-alpha toxin titers. Titers observed during in vivo and in vitro seroneutralization had a correlation of 99.12%, indicating that cell culture is a viable alternative in the evaluation of vaccine potency, screening of vaccinal seeds, and Clostridium septicum alpha toxin titration.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Seroneutralization; Mouse; Guinea pig; Cell culture; Vaccine.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352010000400002

Relaxant effects of different fractions from Tymus vulgaris on guinea-pig tracheal chains
Provedor de dados: 48
Autores: Keyhanmanesh,Rana; Boskabady,Mohammad H.
In previous studies, the relaxant effect of Tymus vulgaris has been demonstrated on guinea pig tracheal chains. Therefore, in the present study, the relaxant effects of n-hexane, dichloromethane, methanol and aqueous fractions of Tymus vulgaris on tracheal chains of guinea pigs were examined. The relaxant effects of four cumulative concentrations of each fraction (0.4, 0.8, 1.2 and 1.6 g%) in comparison to saline as negative control and four cumulative concentrations of theophylline (0.2, 0.4, 0.6 and 0.8 mM) were examined for their relaxant effects on precontracted tracheal chains of guinea pig by 60 mM KCl (group 1) and 10 ìÌ methacholine (group 2, n = 7 for each group). In group 1, all concentrations of the n-hexane fraction and theophylline and three...
Tipo: Journal article
Palavras-chave: Tymus vulgaris; Fractions; Relaxant effects; Guinea pig; Trachea.
Ano: 2012
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100009

Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
Provedor de dados: 52
Autores: Rady,Mohamed Ibrahim.
The present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily, diazinon insecticide oral LD50 was investigated after administrating orally different doses in guinea pig and was determined as 213 mg/Kg bw., the animals exposed to sub lethal doses of this insecticide revealed histological changes in both lung and intestine in a dose dependent manner. Also, significant decrease in the total protein and general carbohydrates in the lung and intestine were mostly observed, especially with the higher doses of the insecticide in...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Diazinon; Guinea pig; Lung; Intestine.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008

Inotropic effects of extracts of Psidium guajava L. (guava) leaves on the guinea pig atrium
Provedor de dados: 56
Autores: Conde Garcia,E.A.; Nascimento,V.T.; Santiago Santos,A.B.
Many pharmacological effects have been ascribed to extracts of Psidium guajava L. (guava) leaves. However, in spite of its widespread use in Brazilian folk medicine and a reasonable number of scientific reports about it, we could not find any study dealing with its action on the mammalian myocardium. In the present study, by measuring isometric force, we observed that the crude extract of P. guajava (water-alcohol extract obtained by macerating dry leaves) depresses the guinea pig atrial contractility in a concentration-dependent fashion (N = 8 hearts, 15 trials). The compound with cardiac activity was concentrated by extraction in a Soxhlet apparatus using 17 M glacial acetic acid after removing the less polar fractions (hexane, chloroform, acetone,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Heart contractility; Guinea pig; Myocardial inotropism; Psidium guajava L.; Folk medicine.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500014

Endogenous opiate analgesia induced by tonic immobility in guinea pigs
Provedor de dados: 56
Autores: Leite-Panissi,C.R.A.; Rodrigues,C.L.; Brentegani,M.R.; Menescal-de-Oliveira,L.
A function of the endogenous analgesic system is to prevent recuperative behaviors generated by tissue damage, thus preventing the emission of species-specific defensive behaviors. Activation of intrinsic nociception is fundamental for the maintenance of the behavioral strategy adopted. Tonic immobility (TI) is an inborn defensive behavior characterized by a temporary state of profound and reversible motor inhibition elicited by some forms of physical restraint. We studied the effect of TI behavior on nociception produced by the formalin and hot-plate tests in guinea pigs. The induction of TI produced a significant decrease in the number of flinches (18 ± 6 and 2 ± 1 in phases 1 and 2) and lickings (6 ± 2 and 1 ± 1 in phases 1 and 2) in the formalin test...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Tonic immobility; Guinea pig; Antinociception; Opioids; Naloxone; Analgesia.
Ano: 2001
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200013