Consulta: subjectFacets:"HBV mutation"
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Data/hora: 13/06/2024 14:25:15

Hepatitis B virus in the State of Alagoas, Brazil: genotypes characterization and mutations of the precore and basal core promoter regions
Provedor de dados: 55
Autores: Eloy,Alba Maria Xavier; Moreira,Regina Célia; Lemos,Marcílio Figueiredo; Silva,Jéfferson Luis de Almeida; Coêlho,Maria Rosângela Cunha Duarte.
The aims of this study were to investigate the genotypes of hepatitis B virus and to identify the precore G1896A and basal core promoter A1762T/G1764A mutations in HBsAg and anti-HBc-positive patients. Eighty-three asymptomatic individuals, three with acute hepatitis B and 33 with chronic hepatitis B referred to viral hepatitis centers in the State of Alagoas, Brazil were analyzed according to their viral load, HBeAg/anti-HBe profile and alanine aminotransferase serum level. The genotypes identified were: A (92.5%), C (5%), D (1.25%) and F (1.25%). The precore mutation was detected in 3.8% of sequences and basal core promoter mutation in 52.4%. These were identified in 45.45% of the asymptomatic individuals and 54.55% of the patients with chronic...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Genotypes; HBV mutation; Alagoas; Brazil.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600013