Consulta: subjectFacets:"HPA axis"
Registros recuperados: 3
Data/hora: 09/06/2024 04:08:53

Reproductive Response in Offspring Male Rats Exposed to Prenatal Stress and to Early Postnatal Stimulation
Provedor de dados: 77
Autores: Chen Cárdenas,S. M; Mayer,N; Romanini,M. C; Rolando,A. N; Liaudat,A. C; Brun,N; Vivas,A; Gauna,H. F; Rodríguez,N.
Stress in pregnant rats alters the pattern of secretion of corticosterone (COR) and modifies transplacentally hypothalamic-pituitary-adrenal axis (HPA) fetus. Prenatal stress during the critical hypothalamic differentiation is related to decreased fertility of male offspring by an increase in the basal level of COR. This modification could induce long-term changes in the process of apoptosis in the testis. However, early postnatal handling increases maternal behavior and could reverse the effects caused by increased secretion of COR. The aim of this research was to investigate the effects of early postnatal stimulation of male rats prenatal stressed by chronic immobilization during the last two weeks of pregnancy, on the hypothalamic-pituitary-gonadal axis...
Tipo: Journal article
Palavras-chave: Early postnatal stimulation; Prenatal stress; HPA axis; HPG axis; Rats; Apoptosis.
Ano: 2013
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200065

Effect of cyhalothrin on Ehrlich tumor growth and macrophage activity in mice
Provedor de dados: 56
Autores: Quinteiro-Filho,W.M.; Righi,D.A.; Palermo-Neto,J.
Cyhalothrin, a pyrethroid insecticide, induces stress-like symptoms, increases c-fos immunoreactivity in the paraventricular nucleus of the hypothalamus, and decreases innate immune responses in laboratory animals. Macrophages are key elements in cellular immune responses and operate at the tumor-host interface. This study investigated the relationship among cyhalothrin effects on Ehrlich tumor growth, serum corticosterone levels and peritoneal macrophage activity in mice. Three experiments were done with 10 experimental (single gavage administration of 3.0 mg/kg cyhalothrin daily for 7 days) and 10 control (single gavage administration of 1.0 mL/kg vehicle of cyhalothrin preparation daily for 7 days) isogenic BALB/c mice in each experiment. Cyhalothrin i)...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cyhalothrin; Corticosterone; Macrophage; Ehrlich tumor; Innate immunity; HPA axis.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000006

Different levels of brain-derived neurotrophic factor and cortisol in healthy heavy smokers
Provedor de dados: 56
Autores: Neves,C.D.C.; Lacerda,A.C.R.; Lima,L.P.; Lage,V.K.S.; Balthazar,C.H.; Leite,H.R.; Mendonça,V.A.
Studies suggest that brain-derived neurotrophic factor (BDNF) and the hypothalamic-pituitary-adrenal (HPA) axis modulate dopaminergic activity in response to nicotine and that the concentrations of BDNF and cortisol seem to be dependent on the amount and duration of smoking. Therefore, we investigated BDNF and cortisol levels in smokers ranked by daily cigarette consumption. Twenty-seven adult males (13 non-smokers and 14 smokers) participated in the study. The smokers were divided in two groups: light (n=7) and heavy smokers (n=7). Anthropometric parameters and age were paired between the groups, and plasma BDNF and salivary cortisol levels were measured. Saliva samples were collected on awakening, 30 min after awakening, at 10:00 and 12:00 am, 5:00 and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: BDNF; Nicotine consumption; HPA axis; Addiction; Reward system.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001200608