Consulta: subjectFacets:"Haemophilus ducreyi"
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A comparative study of single-dose treatment of chancroid using thiamphenicol versus Azithromycin
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: B. Junior,Walter; Di Chiacchio,Nilton G.; Di Chiacchio,Nilton; Romiti,Ricardo; Criado,Paulo R.; Velho,Paulo Eduardo N. Ferreira.
A study was conducted in São Paulo, Brazil, to compare azithromycin with thiamphenicol for the single-dose treatment of chancroid. In all, 54 men with chancroid were tested. The etiology was determined by clinical characterization and direct bacterioscopy with Gram staining. None of the patients had positive serology or dark-field examination indicating active infection with Treponema pallidum. Genital infections due to Neisseria gonorrhoeae and herpes simplex virus were excluded by polymerase chain reaction testing. For 54 patients with chancroid, cure rates with single-dose treatment were 73% with azithromycin and 89% with thiamphenicol. HIV seropositivity was found to be associated with treatment failure (p=0.001). The treatment failed in all HIV...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Azithromycin; Chancroid; Haemophilus ducreyi; Single dose; Thiamphenicol.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300012