Consulta: subjectFacets:"Haemophilus influenzae type b"
Registros recuperados: 2
Data/hora: 10/06/2024 12:10:54

Placental transfer of Haemophilus influenzae type b antibodies in malnourished pregnant women
Provedor de dados: 55
Autores: Cavalcante,Rejane S.; Kopelman,Benjamin I.; Costa-Carvalho,Beatriz T.
This study evaluated the vaccination response to Haemophilus influenzae type b (Hib) in malnourished pregnant women (MN), cord blood (CB) and in infants at two and six months of age for comparison with a control group (C). Twenty-eight malnourished pregnant women and 29 pregnant controls were immunized with conjugated Act-HIB® in the third trimester of pregnancy. Blood samples were collected from all before the immunization, during labor (post immunization), and from CB. All infants were immunized with Hib vaccine according to normal vaccine schedule and sera were collected at two and six months of age. Antibody levels to polyribosylribitol phosphate (PRP) were similar for both groups. Preimmunization: MN 1.94 µg/mL, C 1.68 µg/mL; post-vaccination: MN...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Pregnant women; Malnourished; Haemophilus influenzae type b; Passive immunization; Vaccine; Antibodies; Immunoglobulin G.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100011

Pattern of functional antibody activity against Haemophilus influenzae type b (Hib) in infants immunized with diphtheria-tetanus-pertussis/Hib Brazilian combination vaccine
Provedor de dados: 56
Autores: Matos,D.C.S.; Silva,A.M.V.; Neves,P.C.C.; Martins,R.M.; Homma,A.; Marcovistz,R.
We evaluated the functional activity of Haemophilus influenzae B (Hib) antibodies elicited in a group of infants immunized with the diphtheria-tetanus-pertussis vaccine combined with an Hib vaccine produced totally in Brazil after technological transfer of Hib vaccine production from Glaxo SmithKline, Belgium. Blood samples from immunized infants (N = 985) were collected for the determination of Hib antibodies. Total Ig and IgM and IgG subclasses of antibodies against polyribosyl ribitol phosphate (PRP) were analyzed by ELISA. Almost all vaccinees (97.56%, 961/985) developed a strong anti-PRP IgG antibody response (≥1.0 μg/mL), while an anti-PRP IgM response was observed in 64.24% (634/985) of them (≥0.15 μg/mL). Only 18.88% (186/985) of the infants in the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: DTP-Hib vaccine; Haemophilus influenzae type b; Antibody avidity; PRP immune response.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200020