Consulta: subjectFacets:"Host-pathogen interaction"
Registros recuperados: 8
Data/hora: 04/06/2024 09:32:39

A preliminary survey of M. hyopneumoniae virulence factors based on comparative genomic analysis
Provedor de dados: 74
Autores: Ferreira,Henrique Bunselmeyer; Castro,Luiza Amaral de.
Mycoplasma hyopneumoniae is the etiological agent of porcine enzootic pneumonia (PEP), a major problem for the pig industry. The mechanisms of M. hyopneumoniae pathogenicity allow to predict the existence of several classes of virulence factors, whose study has been essentially restricted to the characterization of adhesion-related and major antigenic proteins. The now available complete sequences of the genomes of two pathogenic and one non-pathogenic strain of M. hyopneumoniae allowed to use a comparative genomics approach to putatively identify virulence genes. In this preliminary survey, we were able to identify 118 CDSs encoding putative virulence factors, based on specific criteria ranging from predicted cell surface location or variation between...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Porcine enzootic pneumoniae; Virulence; Host-pathogen interaction; Antigen; Adhesin.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200012

High temperature induces transcriptomic changes in   Crassostrea gigas   that hinder progress of ostreid herpesvirus (OsHV-1) and promote survival
Provedor de dados: 5
Autores: Delisle, Lizenn; Pauletto, Marianna; Vidal-dupiol, Jeremie; Petton, Bruno; Bargelloni, Luca; Montagnani, Caroline; Pernet, Fabrice; Corporeau, Charlotte; Fleury, Elodie.
Of all environmental factors, seawater temperature plays a decisive role in triggering marine diseases. Like fever in vertebrates, high seawater temperature could modulate the host response to pathogens in ectothermic animals. In France, massive mortality of Pacific oysters, Crassostrea gigas, caused by the ostreid herpesvirus 1 (OsHV-1) is markedly reduced when temperatures exceed 24°C in the field. In the present study we assess how high temperature influences the host response to the pathogen by comparing transcriptomes (RNA sequencing) during the course of experimental infection at 21°C (reference) and 29°C. We show that high temperature induced host physiological processes that are unfavorable to the viral infection. Temperature influenced the...
Tipo: Text
Palavras-chave: Anti-viral molecular pathway; Host-pathogen interaction; Marine disease; OsHV-1; Resistance; Temperature.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00656/76806/77974.pdf

Interaction between toxic dinoflagellate Alexandrium catenella exposure and disease associated with herpesvirus OsHV-1μVar in Pacific oyster spat Crassostrea gigas
Provedor de dados: 5
Autores: Lassudrie, Malwenn; Soudant, Philippe; Nicolas, Jean-louis; Fabioux, Caroline; Lambert, Christophe; Miner, Philippe; Le Grand, Jacqueline; Petton, Bruno; Hegaret, Helene.
Blooms of toxic dinoflagellates can co-occur with mass mortality events associated with herpesvirus OsHV-1 μVar infection that have been decimating Pacific oyster Crassostrea gigas spat and juveniles every summer since 2008 in France. This study investigated the possible effect of a harmful dinoflagellate, Alexandrium catenella, a producer of Paralytic Shellfish Toxins (PSTs), upon the oyster spat–herpesvirus interaction. Oyster spat from a hatchery were challenged by cohabitation with oysters contaminated in the field with OsHV-1 μVar and possibly other pathogens. Simultaneously, the oysters were exposed to cultured A. catenella. Infection with OsHV-1 μVar and PST accumulation were measured after 4 days of experimental exposure.  Exposure to Alexandrium...
Tipo: Text
Palavras-chave: Crassostrea gigas; OsHV-1 mu Var; Harmful algal blooms; Alexandrium; Host-pathogen interaction; PST accumulation.
Ano: 2015
URL: https://archimer.ifremer.fr/doc/00269/38000/36101.pdf

Molecular Targets for Coevolutionary Interactions Between Pacific Oyster Larvae and Their Sympatric Vibrios
Provedor de dados: 5
Autores: Wegner, K. Mathias; Piel, Damien; Bruto, Maxime; John, Uwe; Mao, Zhijuan; Alunno-bruscia, Marianne; Petton, Bruno; Le Roux, Frederique.
Bacteria of the Vibrio genus are the most predominant infectious agents threatening marine wildlife and aquaculture. Due to the large genetic diversity of these pathogens, the molecular determinants of Vibrio virulence are only poorly understood. Furthermore, studies tend to ignore co-evolutionary interactions between different host populations and their locally encountered Vibrio communities. Here, we explore the molecular targets of such co-evolutionary interactions by analyzing the genomes of nine Vibrio strains from the Splendidus-clade showing opposite virulence patterns towards two populations of Pacific oysters introduced into European Wadden Sea. By contrasting Vibrio phylogeny to their host specific virulence patterns, we could identify two core...
Tipo: Text
Palavras-chave: Virulence; Host-pathogen interaction; Local adaptation; Biological invasion; Emerging disease; Wadden Sea.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00512/62409/66669.pdf

Use of OmpU porins for attachment and invasion of Crassostrea gigas immune cells by the oyster pathogen Vibrio splendidus
Provedor de dados: 5
Autores: Duperthuy, Marylise; Schmitt, Paulina; Garzon, Edwin; Caro, Audrey; Rosa, Rafael D.; Le Roux, Frederique; Lautredou-audouy, Nicole; Got, Patrice; Romestand, Bernard; De Lorgeril, Julien; Kieffer-jaquinod, Sylvie; Bachere, Evelyne; Destoumieux-garzon, Delphine.
OmpU porins are increasingly recognized as key determinants of pathogenic host Vibrio interactions. Although mechanisms remain incompletely understood, various species, including the human pathogen Vibrio cholera, require OmpU for host colonization and virulence. We have shown previously that OmpU is essential for virulence in the oyster pathogen Vibrio splendidus LGP32. Here, we showed that V. splendidus LGP32 invades the oyster immune cells, the hemocytes, through subversion of host-cell actin cytoskeleton. In this process, OmpU serves as an adhesin/invasin required for beta-integrin recognition and host cell invasion. Furthermore, the major protein of oyster plasma, the extracellular superoxide dismutase Cg-EcSOD, is used as an opsonin mediating the...
Tipo: Text
Palavras-chave: Host-pathogen interaction; Innate immunity; Invertebrate; Mollusk; Oxidative burst.
Ano: 2011
URL: http://archimer.ifremer.fr/doc/00031/14177/12166.pdf

Different survival of three populations of European sea bass (Dicentrarchus labrax) following challenge with two variants of nervous necrosis virus (NNV)
Provedor de dados: 5
Autores: Barsøe, Sofie; Allal, Francois; Vergnet, Alain; Vandeputte, Marc; Olesen, Niels Jørgen; Schmidt, Jacob Günther; Larsen, Cathrine Agnete; Cuenca, Argelia; Vendramin, Niccolò.
Viral Nervous Necrosis (VNN, also called viral encephalo- and retinopathy (VER)), is a widespread disease of marine aquaculture caused by betanodavirus (or nervous necrosis virus - NNV), a segmented positive sense RNA virus, member of the nodaviridae family. VNN affects predominantly marine fish and cause significant losses to the Mediterranean fish farming industry, including the production of European sea bass (Dicentrarchus labrax). Of the four circulating genotypes of betanodavirus, red-spotted grouper NNV (RGNNV) and the reassortant genotype red-spotted grouper/striped jack NNV (RG/SJNNV) are most prevalent in the Mediterranean. Inheritable resistance against VNN has been detected in sea bass, and selective breeding could be a mean to limit this...
Tipo: Text
Palavras-chave: Nervous necrosis virus; Betanodavirus; Viral enchephalo-and retinopathy; Genetic resistance; Host-pathogen interaction; Sea bass; Neurological infection.
Ano: 2021
URL: https://archimer.ifremer.fr/doc/00678/79050/81498.pdf

INTERACCIÓN PLANTA-BACTERIAS FITOPATÓGENAS: CASO DE ESTUDIO RALSTONIA SOLANACEARUM- PLANTAS HOSPEDANTES
Provedor de dados: 100
Autores: González,Ivonne; Arias,Yailén; Peteira,Belkis.
Ralstonia solanacearum (Smith) Yabuuchi es el agente causal de la marchitez bacteriana. Esta enfermedad afecta a numerosos cultivos de importancia económica tales como: tomate, papa, tabaco, banana, berenjena y algunas plantas ornamentales, especialmente en las zonas tropicales y subtropicales. La amplia gama de hospedantes, su distribución y elevada variabilidad, hacen difícil el control de la enfermedad. En este trabajo se exponen los mecanismos de patogenicidad de esta bacteria, así como los mecanismos moleculares mediante los cuales se ejerce la resistencia natural e inducida en la planta.
Tipo: Journal article
Palavras-chave: Host-pathogen interaction; Ralstonia solanacearum; Avirulence genes; Defense mechanisms.
Ano: 2009
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1010-27522009000200001

Soil microorganisms and plant diseases associated to cocoa (Theobroma cacao L.) genotypes in the Ecuadorian Amazon
Provedor de dados: 109
Autores: Freile-Almeida,Jorge Antonio; Morgado-Martínez,Mirna; Pérez-García,Guillermo Armando; Alemán-Pérez,Reinaldo Demesio; Domínguez-Brito,Javier.
Abstract The aim of this research was to analyze the relationship between soil microorganisms and the major diseases affecting promising clones of cocoa (Theobroma cacao L.) in the Ecuadorian Amazon. The EET-95, EET-96, EET-103 and CCN-51 cocoa clones were evaluated, respectively, the latter used as a control, for this, the amount of bacteria, fungi and total actinomycetes, expressed in colony forming units (CFU) per soil gram, was determined, present in the soil rhizosphere of the three cocoa clones, as well as the appearance of the major plant diseases which attacks the cocoa crop. Data were statistically analyzed by one-way ANOVA and Tukey HSD test p&lt;0.05. The bacteria were the microorganisms with the greatest association to the evaluated cocoa...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cocoa rhizosphere; Cocoa yield; Host-pathogen interaction; Microbial ecology; Parasitic fungus; Soil biota.
Ano: 2018
URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-28122018000100023