Consulta: subjectFacets:"Humoral immunity"
Registros recuperados: 7
Data/hora: 08/06/2024 10:44:13

Cecropins as a marker of Spodoptera frugiperda immunosuppression during entomopathogenic bacterial challenge
Provedor de dados: 5
Autores: Duvic, B.; Jouan, V.; Essa, N.; Girard, P-a; Pages, S.; Khattar, Z. Abi; Volkoff, N-a; Givaudan, A.; Destoumieux-garzon, Delphine; Escoubas, Jean-michel.
An antimicrobial peptide (AMP) of the cecropin family was isolated by HPLC from plasma of the insect pest, Spodoptera frugiperda. Its molecular mass is 3910.9 Da as determined by mass spectrometry. Thanks to the EST database Spodobase, we were able to describe 13 cDNAs encoding six different cecropins which belong to the sub-families CecA, CecB, CecC and CecD. The purified peptide identified as CecB1 was chemically synthesized (syCecB1). It was shown to be active against Gram-positive and Gram-negative bacteria as well as fungi. Two closely related entomopathogenic bacteria, Xenorhabdus nematophila F1 and Xenorhabdus mauleonii VC01(T) showed different susceptibility to syCecB1. Indeed, X. nematophila was sensitive to syCecB1 whereas X. mauleonii had a...
Tipo: Text
Palavras-chave: Humoral immunity; Innate immunity; Immunosuppression; Lepidopteran; Invertebrate.
Ano: 2012
URL: http://archimer.ifremer.fr/doc/00086/19728/17485.pdf

Effect of inoculation route on the production of antibodies and histological characteristics of the spleen in laying hens
Provedor de dados: 89
Autores: Eto,SF; Andrade,FG; Pinheiro,JW; Balarin,MR; Ramos,SP; Venancio,EJ.
Recent studies have reported the use of IgY antibody in the prevention or treatment of diseases in animals. IgY can be obtained in large amounts from the yolk of chicken eggs through a low-cost process. This study evaluated the effect of different routes of inoculation on antibody production and spleen morphological characteristics of laying hens (White Leghorn) inoculated with sheep red blood cells. The analysis of the results showed that the intramuscular route is the most efficient for total antibody production in the primary immune response, while the intravenous route is the most efficient in producing IgY antibodies in the secondary immune response. No histological changes were observed in the spleen of laying hens. This study could be useful for...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antibody production; Humoral immunity; IgY; Laying; Spleen.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2012000100011

GLUTAMIC ACID IMPROVES BODY WEIGHT GAIN AND INTESTINAL MORPHOLOGY OF BROILER CHICKENS SUBMITTED TO HEAT STRESS
Provedor de dados: 89
Autores: Porto,ML; Givisiez,PEN; Saraiva,EP; Costa,FGP; Moreira Filho,ALB; Andrade,MFS; Brandão,PA; Guerra,RR.
ABSTRACTThe objective of this study was to evaluate the effects of 1% dietary glutamic acid on the body weight, intestinal morphometry, and anti-Newcastle antibody titers of broiler chickens submitted to heat stress. One-d-old male broiler chicks (n=120) were distributed according to a 2 x 2 factorial design with two environmental temperatures (thermoneutral or heat stress) and two diets (with 0 or 1% glutamic acid). Heat stress temperature was constantly maintained (24h/day) 5 ºC higher than the thermoneutral temperature. Diets supplied the nutritional requirements of broilers in the pre-starter (1 to 7d) and starter (8 to 21d) phases. Birds were vaccinated against Newcastle disease on d 7 via eye drop. On days 5, 10, 15, and 20, individual body weight...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Amino acid; Duodenum morphology; Environmental temperature; Humoral immunity; Heat stress; Performance.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000300355

Serum bactericidal activity as indicator of innate immunity in pacu Piaractus mesopotamicus (Holmberg, 1887)
Provedor de dados: 45
Autores: Biller-Takahashi,J.D.; Takahashi,L.S.; Pilarski,F.; Sebastião,F.A.; Urbinati,E.C.
The immune system of teleost fish has mechanisms responsible for the defense against bacteria through protective proteins in several tissues. The protein action can be evaluated by serum bactericidal activity and this is an important tool to analyze the immune system. Pacu, Piaractus mesopotamicus, is one of the most important fish in national aquaculture. However there is a lack of studies on its immune responses. In order to standardize and assess the accuracy of the serum bactericidal activity assay, fish were briefly challenged with Aeromonas hydrophila and sampled one week after the challenge. The bacterial infection increased the concentration of protective proteins, resulting in a decrease of colony-forming unit values expressed as well as an...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fish innate immunology; Methodology; Humoral immunity.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000600023

An Alternative Inactivant for Rift Valley Fever Virus using Cobra Venom-derived L-Amino Oxidase, which is Related to its Immune Potential
Provedor de dados: 52
Autores: Al-Olayan,Ebtesam M; Mohamed,Aly F; El-Khadraqy,Manal F; Shebl,Rania I; Yehia,HanryM.
ABSTRACT Vaccine improvement depends on the formulation, adjuvant type and inactivant used. The type of formulation may interfere with immunogenicity. The present work aimed to evaluate the inactivation activity and related immune potential of the Cobra venom-derived LAO enzyme compared to the currently used inactivants (BPL and formalin) for both animal and human vaccines. The RVF virus was completely inactivated within 6 hrs, 4 hrs and 2 hrs after treatment with Formalin, LAO and BPL, respectively. The vaccine potency [ED50] was arranged in a descending order from formalin (0.016) to BPL (0.005) and LAO (0.002). The total IgG levels, Neutralizing Index (NI) and Interferon levels were significantly increased compared to those detected after immunization...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rift Valley fever; Inactivant; Humoral immunity; Interferon; Interleukins; LAO.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100345

Humoral immune response to measles and varicella vaccination in former very low birth weight preterm infants
Provedor de dados: 55
Autores: Ferreira,Carolina Schlindwein Mariano; Perin,Maria Cristina Abrão Aued; Moraes-Pinto,Maria Isabel de; Simão-Gurge,Raquel Maria; Goulart,Ana Lucia; Weckx,Lily Yin; dos Santos,Amélia Miyashiro Nunes.
ABSTRACT  Introduction: Immune response to vaccination in infants born prematurely may be lower than in infants born at full-term. Some clinical factors might be associated with humoral immune response.  Objectives: The objectives of this study were to compare the immune response to measles and varicella vaccination in infants born prematurely with those born at full-term and to analyze factors associated with measles and varicella antibody levels.  Methods: Prospective study including two groups of infants aged 12 months. One group of infants born prematurely with birth-weight &lt;1500 g and who were in follow-up at the outpatient clinic for preterm infants at the institution and other group of infants born at full-term. Infants with malformations,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Premature; Vaccination; Humoral immunity; Measles; Varicella.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000100041

Follicular helper T cell in immunity and autoimmunity
Provedor de dados: 56
Autores: Mesquita Jr,D.; Cruvinel,W.M.; Resende,L.S.; Mesquita,F.V.; Silva,N.P.; Câmara,N.O.S.; Andrade,L.E.C.
The traditional concept that effector T helper (Th) responses are mediated by Th1/Th2 cell subtypes has been broadened by the recent demonstration of two new effector T helper cells, the IL-17 producing cells (Th17) and the follicular helper T cells (Tfh). These new subsets have many features in common, such as the ability to produce IL-21 and to express the IL-23 receptor (IL23R), the inducible co-stimulatory molecule ICOS, and the transcription factor c-Maf, all of them essential for expansion and establishment of the final pool of both subsets. Tfh cells differ from Th17 by their ability to home to B cell areas in secondary lymphoid tissue through interactions mediated by the chemokine receptor CXCR5 and its ligand CXCL13. These CXCR5+ CD4+ T cells are...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Autoimmune diseases; Tfh; Lymphoid tissue; Humoral immunity.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500302