Consulta: subjectFacets:"Lipoprotein oxidation"
Registros recuperados: 2
Data/hora: 04/06/2024 01:09:34

Lipid peroxidation and antioxidants in hyperlipidemia and hypertension
Provedor de dados: 48
Autores: MORIEL,PATRICIA; PLAVNIK,FRIDA L; ZANELLA,MARIA T; BERTOLAMI,MARCELO C; ABDALLA,DULCINEIA SP.
Lipid peroxidation and lipid-derived oxidized products have been implicated in the pathogenesis of a variety of human diseases. To clarify the role of oxidative stress in essential hypertension and hypercholesterolemia the in vitro oxidative susceptibility of LDL, the antioxidant status and the lipid peroxide content of blood plasma were examined in hypercholesterolemic (HC), hypertensive (H), hypercholesterolemic/hypertensive (HH) and normolipidemic/normotensive subjects (N). Plasma ascorbate and lipid-soluble antioxidants were lower, while LDL oxidizability, CE-OOH and TL-OOH were higher in H, HC, and HH groups than in the N group. No difference was observed among groups for PL-OOH and isoprostanes. In summary, the results show that: 1) lipid- and...
Tipo: Journal article
Palavras-chave: Lipoprotein oxidation; Lipid peroxides; Isoprostanes; Antioxidants; Atherosclerosis; Oxidative stress.
Ano: 2000
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200010

Estrogen replacement therapy and cardioprotection: mechanisms and controversies
Provedor de dados: 56
Autores: Subbiah,M.T.R.
Epidemiological and case-controlled studies suggest that estrogen replacement therapy might be beneficial in terms of primary prevention of coronary heart disease (CHD). This beneficial effect of estrogens was initially considered to be due to the reduction of low density lipoproteins (LDL) and to increases in high density lipoproteins (HDL). Recent studies have shown that estrogens protect against oxidative stress and decrease LDL oxidation. Estrogens have direct effects on the arterial tissue and modulate vascular reactivity through nitric oxide and prostaglandin synthesis. While many of the effects of estrogen on vascular tissue are believed to be mediated by estrogen receptors alpha and ß, there is evidence for `immediate non-genomic' effects. The role...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Estrogen therapy; Postmenopausal women; Cardiovascular disease; Plasma lipoproteins; Lipoprotein oxidation; Estrogen receptors; Thrombosis; Nitric oxide synthesis.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000300001