Consulta: subjectFacets:"Monoamine oxidase A"
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Data/hora: 02/06/2024 06:31:16

Molecular identification and expression of two non-P450 enzymes, monoamine oxidase A and flavin-containing monooxygenase 2, involved in phase I of xenobiotic biotransformation in the Pacific oyster, Crassostrea gigas
Provedor de dados: 5
Autores: Boutet, Isabelle; Tanguy, Aurelie; Moraga, Dario.
Marine bivalve metabolism can be perturbed by hydrocarbon and pesticide pollution in coastal ecosystems. In this study, in the Pacific oyster, Crassostrea gigas, full-length cDNAs encoding two non-P450 phase I enzymes, flavin-containing monooxygenase 2 (FMO-2) and monamine oxidase A (MAO A), were characterized. Both sequences contained the co-factor fixation motifs characteristic of their respective enzyme families. Using reverse transcription polymerase chain reaction (RT-PCR), the messenger RNA (mRNA) transcription levels of these two enzymes in tissues of oysters exposed, under experimental conditions, to hydrocarbons and two pesticide treatments were investigated. The pesticide treatments were exposure to either glyphosate or to a mixture composed of...
Tipo: Text
Palavras-chave: Crassostrea gigas; Flavin containing monooxygenase 2; Monoamine oxidase A.
Ano: 2004
URL: http://archimer.ifremer.fr/doc/2004/publication-676.pdf