Consulta: subjectFacets:"Neglected tropical diseases"
Registros recuperados: 2
Data/hora: 09/06/2024 05:45:09

The WHO strategy for prevention and control of snakebite envenoming: a sub-Saharan Africa plan
Provedor de dados: 80
Autores: Chippaux,Jean-Philippe; Massougbodji,Achille; Habib,Abdulrazaq G.
Abstract Snakebite is a critical public health issue in tropical countries, particularly in Africa, where 20% of snakebites globally occur. In 2017, the WHO added snakebite envenoming to the category A of neglected tropical diseases. In 2019, thanks to broad institutional and international NGO support, including strong mobilization of African experts and governments, WHO launched a strategy for prevention and control of snakebite envenoming with more ambitious goals. In sub-Saharan Africa, accessibility of antivenoms and symptomatic, adjuvant or replacement therapy is a priority. Several antivenoms are available but their evaluation has not been properly carried out and they remain expensive. To date, there are no manufacturers of antivenom in sub-Saharan...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Snakebite; Envenomation; Antivenom; Sub-Saharan Africa; Neglected tropical diseases; Control.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100101

From Medicinal Chemistry to Human Health: Current Approaches to Drug Discovery for Cancer and Neglected Tropical Diseases
Provedor de dados: 42
Autores: FERREIRA,LEONARDO G.; OLIVA,GLAUCIUS; ANDRICOPULO,ADRIANO D.
ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprecedentedly demanded the development of up-to-date computational approaches, such as bio- and chemo-informatics. These tools have been pivotal to catalyzing the ever-increasing amount of data generated by the molecular sciences, and to converting the data into insightful guidelines for use in the research pipeline. As a result, ligand- and structure-based drug design have emerged as key pathways to address the pharmaceutical industry’s striking demands for...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Medicinal chemistry; Ligand-based drug design; Structure-based drug design; Cancer; Neglected tropical diseases.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000200645