Consulta: subjectFacets:"Neuroimmunomodulation"
Registros recuperados: 2
Data/hora: 10/06/2024 08:07:58

Dexamethasone Regulates Macrophage and Cd4+Cd25+ Cell Numbers in the Chicken Spleen
Provedor de dados: Revista Brasileira de Ciência Avícola
Autores: Calefi,AS; Quinteiro-Filho,WM; Fukushima,AR; Cruz,DSG da; Siqueira,A de; Salvagni,FA; Namazu,LB; Gomes,COMS; Ferreira,AJP; Palermo Neto,J.
Abstract Dexamethasone (DEX) is a corticoid hormone that is experimentally used to mimic the effects of increased levels of endogenous corticosterone observed during the stress response. Currently, stress is considered one of the major predisposing factors for diseases in the poultry industry. The aim of this study was to analyze the effects of DEX and/or of a 20-fold coccidial vaccine dose on leukocyte phenotypes in the spleen and cecal tonsils of chickens. Twenty specific-pathogen-free (SPF) Leghorn chickens were divided into four groups: a non-treated group (NT), a DEX-treated group (Dex), a vaccinated group (V) and a DEX-treated+vaccinated group (Dex+V). On experimental day (ED) 42, each bird in the vaccinated groups received a anti-coccidial vaccine....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Coccidiosis; Eimeria; Avian immunology; Flow cytometry; Neuroimmunomodulation.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2016000100093

Fever induction pathways: evidence from responses to systemic or local cytokine formation
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Roth,J.; de Souza,G.E.P.
The immune and central nervous systems are functionally connected and interacting. The concept that the immune signaling to the brain which induces fever during infection and inflammation is mediated by circulating cytokines has been traditionally accepted. Administration of bacterial lipopolysaccharide (LPS) induces the appearance of a so-termed "cytokine cascade" in the circulation more or less concomitantly to the developing febrile response. Also, LPS-like fever can be induced by systemic administration of key cytokines (IL-1ß, TNF-alpha, and others). However, anti-cytokine strategies against IL-1ß or TNF-alpha along with systemic injections of LPS frequently lead to attenuation of the later stages of the febrile response but not of the initial phase...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fever; Cytokines; Neuroimmunomodulation; Humoral factors; Afferent nerves; Central nervous system.
Ano: 2001
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300003