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Methylmercury intoxication and histochemical demonstration of NADPH-diaphorase activity in the striate cortex of adult cats
Provedor de dados: 56
Autores: Oliveira,R.B.; Gomes-Leal,W.; do-Nascimento,J.L.M.; Picanço-Diniz,C.W.
The effects of methylmercury (MeHg) on histochemical demonstration of the NADPH-diaphorase (NADPH-d) activity in the striate cortex were studied in 4 adult cats. Two animals were used as control. The contaminated animals received 50 ml milk containing 0.42 µg MeHg and 100 g fish containing 0.03 µg MeHg daily for 2 months. The level of MeHg in area 17 of intoxicated animals was 3.2 µg/g wet weight brain tissue. Two cats were perfused 24 h after the last dose (group 1) and the other animals were perfused 6 months later (group 2). After microtomy, sections were processed for NADPHd histochemistry procedures using the malic enzyme method. Dendritic branch counts were performed from camera lucida drawings for control and intoxicated animals (N = 80). Average,...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: NADPH-dehydrogenase; Visual cortex; Neurotoxicity; Neuropil; Mercury.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000900009