Consulta: subjectFacets:"Nociceptive response"
Registros recuperados: 2
Data/hora: 16/06/2024 11:17:01

Composition and biological activities of the aqueous extracts of three scleractinian corals from the Mexican Caribbean: Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea
Provedor de dados: 80
Autores: García-Arredondo,Alejandro; Rojas-Molina,Alejandra; Ibarra-Alvarado,César; Lazcano-Pérez,Fernando; Arreguín-Espinosa,Roberto; Sánchez-Rodríguez,Judith.
Abstract  Background: Scleractinian corals (stony corals) are the most abundant reef-forming cnidarians found in coral reefs throughout the world. Despite their abundance and ecological importance, information about the diversity of their toxins and their biological activities is very scarce. In this study, the chemical composition and the biological activities of the aqueous extracts of Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea, three scleractinian corals from the Mexican Caribbean, have been assessed for the first time.  Methods: Toxicity of the extracts was assessed in crickets; the presence of cytolysins was detected by the hemolysis assay; the vasoconstrictor activity was determined by the isolated rat aortic ring assay; the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Scleractinia; Pseudodiploria strigosa; Porites astreoides; Siderastrea siderea; Toxicity; Hemolysis; Vasoconstriction; Nociceptive response.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100323

Chronic intrathecal cannulation enhances nociceptive responses in rats
Provedor de dados: 56
Autores: Almeida,F.R.C.; Schivo,I.R.S.; Lorenzetti,B.B.; Ferreira,S.H.
The influence of a chronically implanted spinal cannula on the nociceptive response induced by mechanical, chemical or thermal stimuli was evaluated. The hyperalgesia in response to mechanical stimulation induced by carrageenin or prostaglandin E2 (PGE2) was significantly increased in cannulated (Cn) rats, compared with naive (Nv) or sham-operated (Sh) rats. Only Cn animals presented an enhanced nociceptive response in the first phase of the formalin test when low doses were used (0.3 and 1%). The withdrawal latency to thermal stimulation of a paw inflamed by carrageenin was significantly reduced in Cn rats but not in Nv or Sh rats. In contrast to Nv and Sh rats, injection in Cn animals of a standard non-steroid anti-inflammatory drug, indomethacin, either...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Hyperalgesia; Spinal sensitization; Intrathecal cannulation; Nociceptive response; Inflammation.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000800011