Consulta: subjectFacets:"Pharmaceutical"
Registros recuperados: 3
Data/hora: 09/06/2024 01:41:36

Joint effects of nine antidepressants on Raphidocelis subcapitata and Skeletonema marinoi : a matter of amine functional groups
Provedor de dados: 5
Autores: Minguez, Laetitia; Bureau, Ronan; Halm-lemeille, Marie-pierre.
Antidepressants are among the most prescribed pharmaceuticals throughout the world. Their presence has already been detected in several aquatic ecosystems worldwide and their effects on non-target organisms justify the growing concern of both the public and regulatory authorities. These emerging pollutants do not occur as isolated compounds but rather as multi-component mixtures, which may lead to increased adverse effects compared to individual compounds. Freshwater and marine algae seem particularly sensitive to pharmaceuticals, including antidepressants. Studies assessing the toxicity of antidepressant mixture to algae focused mainly on binary mixtures of selective serotonin reuptake inhibitors. In the present experiment, the freshwater algae...
Tipo: Text
Palavras-chave: Green algae; Diatom; Mixture; Pharmaceutical; QSAR.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00423/53429/54315.pdf

Impact of piperacillin-tazobactam shortage on meropenem use: implications for antimicrobial stewardship programs
Provedor de dados: 55
Autores: Barber,Katie E.; Bell,Allison M.; King,S. Travis; Parham,Jason J.; Stover,Kayla R.
ABSTRACT Drug shortages pose a clear detriment to antimicrobial stewardship (AS) efforts. Our objective was to evaluate the effect of a piperacillin-tazobactam shortage on meropenem use, related costs, and associated changes in AS activity. A quasi-experimental quality improvement review compared adult patients receiving meropenem ≥72 h three months pre-shortage and three months during the shortage. 320 patients were included (pre-shortage: 103; shortage: 217). Baseline characteristics were similar, but the length of stay was slightly longer in pre-shortage [19 (11-32) days] versus shortage [16 (11-32) days] (p = 0.094). In pre-shortage and shortage, median days of therapy and estimated meropenem cost were 7 (5-11) and 7 (5-10) and $309.93...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Piperacillin; Meropenem; Pharmaceutical; Antimicrobial stewardship program.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600631

Antimicrobial potential of pyroligneous extracts – a systematic review and technological prospecting
Provedor de dados: 58
Autores: Souza,Juliana Leitzke Santos de; Guimarães,Victoria Burmann da Silva; Campos,Angela Diniz; Lund,Rafael Guerra.
Abstract Pyroligneous extract is applied in diverse areas as an antioxidant, an antimicrobial, and an anti-inflammatory agent. The discovery of new cost-effective antimicrobial agents of natural origin remains a challenge for the scientific community. This study aimed to conduct a systematic review and a technological forecasting of the existent evidence regarding the use of pyroligneous extract as a potential antimicrobial agent. Studies were identified through an investigation of various electronic databases: PubMed, SciFinder, Web of Science, Scopus, Scielo, Google scholar, and ProQuest. Patents were searched through INPI, Google patents, Espacenet, Patents online, USPTO, and WIPO. The literature on antimicrobial activity of pyroligneous extract are...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Food preservation; Antimicrobial; Infections; Preservative; Pharmaceutical.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000500128