Consulta: subjectFacets:"Rosmarinic acid"
Registros recuperados: 3
Data/hora: 08/06/2024 17:21:32

Variation in concentrations of major bioactive compounds in Prunella vulgaris L. related to plant parts and phenological stages
Provedor de dados: 48
Autores: Chen,Yuhang; Zhu,Zaibiao; Guo,Qiaosheng; Zhang,Lixia; Zhang,Xiaoming.
Prunella vulgaris L. (Labiatae) contains a variety of structurally diverse natural products, primarily rosmarinic acid (RA), ursolic acid (UA) and oleanolic acid (OA), which possess a wide array of biological properties. In the present study, P. vulgaris was harvested at three developmental stages (vegetative, full-flowering and mature-fruiting stages), dissected into stem and leaf tissues and assayed for chemical contents using high performance liquid chromatography. Significant changes in the concentrations of the major secondary metabolites (RA, UA and OA) were observed at the different development stages. The highest concentrations of RA, UA and OA were found at the full-flowering stage (15.83 mg/g dry weight (DW) RA, 1.77 mg/g DW UA and 0.65 mg/g DW...
Tipo: Journal article
Palavras-chave: Prunella vulgaris L.; Ontogenetic and morphogenetic variation; Rosmarinic acid; Ursolic acid; Oleanolic acid.
Ano: 2012
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000200009

Effect of a rosmarinic acid supplemented hemodialysis fluid on inflammation of human vascular endothelial cells
Provedor de dados: 56
Autores: Wang,W-J.; Cheng,M-H.; Lin,J-H.; Weng,C-S.
Chronic systemic inflammation and repetitive damage of vascular endothelia by incompatible dialysis system are probable causes of cardiovascular disease in patients on dialysis. The present study aimed to assess in vitro biocompatibility and anti-inflammatory effect of hemodialysis fluid supplemented with rosmarinic acid (RA) using human umbilical vein endothelial cells (HUVEC). HUVECs (5×106 cells/mL) were pre-exposed to 1 μg/mL of lipopolysaccharides (LPS) and incubated with RA-supplemented hemodialysis fluid (HDF). Cytotoxicity was assessed qualitatively by morphologic assessment and quantitatively by MTT assay. Expressions of proinflammatory mediators were assessed using quantitative real-time PCR and production of NO was quantified. Phosphorylation of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rosmarinic acid; Hemodialysis fluid; Anti-inflammation; Endothelial cells; LPS.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001200606

Quantification of chlorogenic acid, rosmarinic acid, and caffeic acid contents in selected Thai medicinal plants using RP-HPLC-DAD
Provedor de dados: 60
Autores: Chaowuttikul,Chayanon; Palanuvej,Chanida; Ruangrungsi,Nijsiri.
The chlorogenic acid, rosmarinic acid, and caffeic acid contents in 100 selected plants were determined using reversed phase high performance liquid chromatography equipped with diode array detector. The optimum condition was 0.2% phosphoric acid in water (solvent A) and methanol (solvent B) as the mobile phase, which was set at 45% B for 20 minutes at a flow rate of 1.2 mL/min. The column temperature was maintained at 30 ºC and the detection wavelength was 325 nm. Among 100 selected plants, 39.64% contained all 3 compounds, 40.54% contained 2 compounds, 14.41% contained only 1 compound, and 5.41% could not detect any of the 3 compounds. The highest contents of chlorogenic acid, rosmarinic acid, and caffeic acid were found in Lonicera japonica flowering...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chlorogenic acid; Rosmarinic acid; Caffeic acid; RP-HPLC-DAD; Medicinal plant.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100507