Consulta: subjectFacets:"Serjania erecta"
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Data/hora: 08/06/2024 01:33:22

Neutralization of pharmacological and toxic activities of Bothrops jararacussu snake venom and isolated myotoxins by Serjania erecta methanolic extract and its fractions
Provedor de dados: 80
Autores: Fernandes,RS; Costa,TR; Marcussi,S; Bernardes,CP; Menaldo,DL; Rodriguéz Gonzaléz,II; Pereira,PS; Soares,AM.
Most of the snakebites recorded in Brazil are caused by the Bothrops genus. Given that the local tissue damage caused by this genus cannot be treated by antivenom therapy, numerous studies are focusing on supplementary alternatives, such as the use of medicinal plants. Serjania erecta has already demonstrated anti-inflammatory, antiseptic and healing properties. In the current study, the aerial parts of S. erecta were extracted with methanol, then submitted to chromatographic fractionation on a Sephadex LH20 column and eluted with methanol, which resulted in four main fractions. The crude extract and fractions neutralized the toxic activities of Bothrops jararacussu snake venom and isolated myotoxins (BthTX-I and II). Results showed that phospholipase A2,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Medicinal plants; Antiophidian properties; Serjania erecta; Bothrops jararacussu snake venom; Myotoxins.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100011