Consulta: subjectFacets:"Solid tumor"
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Data/hora: 11/06/2024 12:03:33

Evaluation of the antioxidant potential of Copaifera multijuga in Ehrlich tumor-bearing mice
Provedor de dados: Acta Amazonica
Autores: CUNHA,Ana Paula Simões da; BALDISSERA,Luana; PEREIRA,Débora Linsbinski; ALBIERO,Lucineia Reuse; CASTOLDI,Lindsey; SINHORIN,Adilson Paulo; SINHORIN,Valéria Dornelles Gindri.
ABSTRACT Copaifera multijuga, commonly known as copaiba, is popularly used in the form of tea for various conditions due to the presence of antioxidant substances in its composition, which protect cells against damage caused by free radicals. Its oleoresin is also used as an anti-inflammatory and antitumoral agent. The present study investigated the antioxidant effect of the ethanolic extract of copaiba stem bark on Swiss mice inoculated with solid Ehrlich tumors. Mice were inoculated subcutaneously with 1x106 Ehrlich’s tumor cells and treated via gavage with ethanolic extract of copaiba for thirty days, with doses varying between 100 and 200 mg kg-1. Biochemical analyses of enzymatic antioxidants [superoxide dismutase (SOD), catalase (CAT),...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Solid tumor; Oxidative stress; Free radicals; Copaiba; Antineoplasic.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672019000100041