Consulta: subjectFacets:"Splenomegaly"
Registros recuperados: 4
Data/hora: 04/06/2024 18:53:50

Hepatosplenomegaly caused by an extract of cyanobacterium Microcystis aeruginosa bloom collected in the Manguaba Lagoon, Alagoas - Brazil
Provedor de dados: 59
Autores: Porfirio,Zenaldo; Ribeiro,Micheline P.; Estevam,Cicero S.; Houly,Ricardo L. S.; Sant'Ana,Antonio Euzébio G.
Cyanobacteria (Microcystis aeruginosa), which produce powerful hepatotoxic cyclopeptides, were collected and submitted to the determination of toxicity through intraperitoneal injections made in 30 and 90 days-old Swiss albino mice. The liver and the spleen were histopathologically analyzed and the weight and vital signs development were monitored. Test of toxicity resulted in a LD50 of 154.28 mg.Kg-1. M. aeruginosa represented 95% of the analyzed biomass. The ratios between liver weight and body weight in the animal inoculated with a single dose were 6.0% and 7.2%, with multi doses 7.0% and 7.5% and in the control animals 4.0% and 5.0%, for adult and young animals, respectively. There was an accentuated increase in the volume and weight of the spleen, and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Microcystis aeruginosa; Cyanobacteria; Hepatomegaly; Splenomegaly.
Ano: 1999
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000300016

Asymptomatic and symptomatic embolic events in infective endocarditis: associated factors and clinical impact
Provedor de dados: 55
Autores: Monteiro,Thaíssa S.; Correia,Marcelo G.; Golebiovski,Wilma F.; Barbosa,Giovanna Ianini F.; Weksler,Clara; Lamas,Cristiane C.
ABSTRACT  Background: Embolic complications of infective endocarditis are common. The impact of asymptomatic embolism is uncertain.  Objectives: To determine the frequency of emboli due to IE and to identify events associated with embolism.  Methods: Retrospective analysis of an endocarditis database, prospectively implemented, with a post hoc study driven by analysis of data on embolic events. Data was obtained from the International Collaboration Endocarditis case report forms and additional information on embolic events and imaging reports were obtained from the medical records. Variables associated with embolism were analyzed by the statistical software R version 3.1.0.  Results: In the study period, 2006-2011, 136 episodes of definite infective...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Infective endocarditis; Embolism; Asymptomatic embolism; Splenomegaly; Cardiac surgery; Splenectomy.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300240

Hyperreactive malarious splenomegaly and aids: a case report
Provedor de dados: 55
Autores: Tano,Zuleica Naomi; Filho,Chafic Esper Kallas; Breganó,Regina Mitsuka; Pavanelli,Wander Rogério; Ruzon,Uheyna Gancedo.
Malaria is endemic in the North of Brazil. However, Hyperreactive Malarious Splenomegaly (HMS) has been rarely described. Splenomegaly in HIV/Aids infection has a large differential diagnosis, but malaria is a cause of gross splenomegaly, regardless of the HIV status. In this paper, we report the case of a 50-year-old man, HIV positive, with massive splenomegaly and multiple malaria infections in the past. He fulfilled the criteria for HMS, received a short course of anti-malarial treatment and weekly quimioprofilatic Chloroquine. In 9 months, he had great clinical and laboratorial improvement confirming the HMS, a rare diagnosis in Brazil.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Hyperreactivemalarious; Splenomegaly; Aids.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500565

Increased immunohistochemical expression of YKL-40 in the spleen of patients with portal hypertension
Provedor de dados: 56
Autores: Wang,Dong; Lu,Jian-Guo; Wang,Qing; Du,Xi-Lin; Dong,Rui; Wang,Peng; Zhao,Lei; Jiang,Xue; Yuan,Li-Juan.
YKL-40 has been identified as a growth factor in connective tissue cells and also a migration factor in vascular smooth muscle cells. To a large extent, the increase of serum YKL-40 is attributed to liver fibrosis and asthma. However, the relationship of the expression and clinical/prognostic significance of YKL-40 to the splenomegaly of patients with portal hypertension is unclear. In the present study, the expression of YKL-40 was studied by immunohistochemistry in 48 splenomegaly tissue samples from patients with portal hypertension and in 14 normal spleen specimens. All specimens were quickly stored at -80°C after resection. Primary antibodies YKL-40 (1:150 dilution, rabbit polyclonal IgG) and MMP-9 (1:200 dilution, rabbit monoclonal IgG) and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: YKL-40; MMP-9; Splenomegaly; Fibrosis; Portal hypertension; Immunohistochemistry.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300013