Consulta: subjectFacets:"Stem cell therapy"
Registros recuperados: 3
Data/hora: 29/05/2024 01:31:06

Histological and immunohistochemical evaluation of two cell therapy protocols in equine suspensory ligament repair
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Garbin,L.C.; Soares,A.S.; Mendes,H.M.F.; Cassali,G.D.; Vasconcelos,A.C.; Faleiros,R.R.
ABSTRACT This study aimed to histologically evaluate the quality of tissue repair in equine suspensory ligament treated with two cell therapy protocols. All four limbs of six animals were operated simultaneously to remove a fragment in each ligament using a skin biopsy punch. Two days later, intralesional injections were performed using bone marrow mononuclear fraction (BM group), cultivated cells derived from adipose tissue (AT group), saline (positive control group), or no treatment (negative control group), in such way that each horse received all treatments. After sixty days biopsies were performed for histological analysis (H &amp; E, Masson’s trichrome and picrosirius red) and immunohistochemistry analysis (collagen type III). Histological findings...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Stem cell therapy; Desmitis; Hors.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000501469

Awareness and current knowledge of breast cancer
Provedor de dados: Biological Research
Autores: Akram,Muhammad; Iqbal,Mehwish; Daniyal,Muhammad; Khan,Asmat Ullah.
Abstract Breast cancer remains a worldwide public health dilemma and is currently the most common tumour in the globe. Awareness of breast cancer, public attentiveness, and advancement in breast imaging has made a positive impact on recognition and screening of breast cancer. Breast cancer is life-threatening disease in females and the leading cause of mortality among women population. For the previous two decades, studies related to the breast cancer has guided to astonishing advancement in our understanding of the breast cancer, resulting in further proficient treatments. Amongst all the malignant diseases, breast cancer is considered as one of the leading cause of death in post menopausal women accounting for 23% of all cancer deaths. It is a global...
Tipo: Journal article
Palavras-chave: Breast cancer; Chemotherapy; Gene therapy; Stem cell therapy.
Ano: 2017
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100504

p19Arf sensitizes B16 melanoma cells to interferon-β delivered via mesenchymal stem cells in vitro
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Da-Costa,R.C.; Vieira,I.L.; Hunger,A.; Tamura,R.E.; Strauss,B.E.
The immune stimulatory and anti-neoplastic functions of type I interferon have long been applied for the treatment of melanoma. However, the systemic application of high levels of this recombinant protein is often met with toxicity. An approach that provides localized, yet transient, production of type I interferon may overcome this limitation. We propose that the use of mesenchymal stem cells (MSCs) as delivery vehicles for the production of interferon-β (IFNβ) may be beneficial when applied together with our cancer gene therapy approach. In our previous studies, we have shown that adenovirus-mediated gene therapy with IFNβ was especially effective in combination with p19Arf gene transfer, resulting in immunogenic cell death. Here we showed that MSCs...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Gene therapy; Immunotherapy; Stem cell therapy; Adenovirus; P53; Interferon-β.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000300601