Consulta: subjectFacets:"TIMPs"
Registros recuperados: 2
Data/hora: 09/06/2024 02:30:00

Segment­Specific Expression of MMP/TIMP in the Oviduct of Llama (Lama glama) and Gelatinolytic Activity in the Oviductal Fluid
Provedor de dados: 77
Autores: Zampini,Renato; Apichela,Silvana; Sari,Luciana; Angiono,Georgina; Lombardo,Daniel; Miceli,Dora; Argañaraz,Martin.
Oviductal molecules have the potential to improve the reproductive biotechnologies. In camelids, knowledge and assessment of the oviductal environment are necessary to successfully develop species-specific reproductive technologies, especially because of the camelids reproductive particularities. Among the oviductal factors, the matrix metalloproteinases/tissue inhibitor of matrix metalloproteinases system (MMPs/TIMPs) should be investigated more thoroughly due to their participation in reproductive processes. Consequently, the current study assayed gene and protein expression of MMPs throughout the llama oviduct. MMPs zymogen and active forms in the oviductal fluid were also characterized. MMP2 and MMP9 transcripts were detected in ampulla, isthmus,...
Tipo: Journal article
Palavras-chave: Oviduct; Llama; MMPs; TIMPs; Gene expression levels.
Ano: 2017
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200038

Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury
Provedor de dados: 56
Autores: Corbel,M.; Boichot,E.; Lagente,V.
Acute lung injury is characterized by a severe disruption of alveolo-capillary structures and includes a variety of changes in lung cell populations. Evidence suggests the occurrence of rupture of the basement membranes and interstitial matrix remodeling during acute lung injury. The dynamic equilibrium of the extracellular matrix (ECM) under physiological conditions is a consequence of the balance between the regulation of synthesis and degradation of ECM components. Matrix metalloproteinases (MMPs) represent a group of enzymes involved in the degradation of most of the components of the ECM and therefore participate in tissue remodeling associated with pathological situations such as acute lung injury. MMP activity is regulated by proteolytic activation...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Matrix metalloproteinase; TIMPs; Acute lung injury; ARDS; LPS; Extracellular matrix.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700004