Consulta: subjectFacets:"Y-chromosome"
Registros recuperados: 5
Data/hora: 02/06/2024 14:49:08

Uniparental ancestry markers in Chilean populations
Provedor de dados: Genetics and Molecular Biology
Autores: Vieira-Machado,Camilla Dutra; Tostes,Maluah; Alves,Gabrielle; Nazer,Julio; Martinez,Liliana; Wettig,Elisabeth; Pizarro Rivadeneira,Oscar; Diaz Caamaño,Marcela; Larenas Ascui,Jessica; Pavez,Pedro; Dutra,Maria da Graça; Castilla,Eduardo Enrique; Orioli,Ieda Maria.
Abstract The presence of Native Americans, Europeans, and Africans has led to the development of a multi-ethnic, admixed population in Chile. This study aimed to contribute to the characterization of the uniparental genetic structure of three Chilean regions. Newborns from seven hospitals in Independencia, Providencia, Santiago, Curicó, Cauquenes, Valdívia, and Puerto Montt communes, belonging to the Chilean regions of Santiago, Maule, and Los Lagos, were studied. The presence of Native American mitochondrial DNA (mtDNA) haplogroups and two markers present in the non-recombinant region of the Y chromosome, DYS199 and DYS287, indicative of Native American and African ancestry, respectively, was determined. A high Native American matrilineal contribution and...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Uniparental markers; Ancestry; MtDNA; Y-chromosome; ECLAMC.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400573

Uniparental genetic markers in South Amerindians
Provedor de dados: Genetics and Molecular Biology
Autores: Bisso-Machado,Rafael; Bortolini,Maria Cátira; Salzano,Francisco Mauro.
A comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mtDNA) haplogroup was examined in 108 populations and 6,697 persons, and sequencing studies used either the complete mtDNA genome or the highly variable segments 1 and 2. The diversity of the markers made it difficult to establish a general picture of Y-chromosome variability in the populations studied. However, haplogroup Q1a3a* was almost always the most prevalent whereas Q1a3* occurred equally in all regions, which suggested its prevalence among the early...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Genetics; Language and geography; Mitochondrial DNA; Native Americans; South Amerindians; Y-chromosome.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300001

Linkage disequilibrium and diversity for three genomic regions in Azoreans and mainland Portuguese
Provedor de dados: Genetics and Molecular Biology
Autores: Branco,Claudia C.; Pacheco,Paula R.; Cabrol,Ester; Cabral,Rita; Vicente,Astrid M.; Mota-Vieira,Luisa.
Studies on linkage disequilibrium (LD) across the genome and populations have been used in recent years with the main objective of improving gene mapping of complex traits. Here, we characterize the patterns of genetic diversity of HLA loci and evaluate LD (D') extent in three genomic regions: Xq13.3, NRY and HLA. In addition, we examine the distribution of DXS1225-DXS8082 haplotype diversity in Azoreans and mainland Portuguese. Allele distribution has demonstrated that the São Miguel population is genetically very diverse; haplotype analysis revealed 100% discriminatory power for X- and Y-markers and 94.3% for HLA markers. Standardized multiallelic D' in these three genomic regions shows values lower than 0.33, thereby suggesting there is no extensive LD...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Linkage disequilibrium; X-chromosome; Y-chromosome; HLA; São Miguel; Azores.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000200003

Cytogenetic study in natural hybrids of Callithrix (Callitrichidae: Primates) in the Atlantic forest of the state of Rio de Janeiro, Brazil
Provedor de dados: Iheringia Série Zoologia
Autores: Nogueira,Denise M.; Ferreira,Ana Maria R.; Goldschmidt,Beatriz; Pissinatti,Alcides; Carelli,Juliane B.; Verona,Carlos E.
In the Atlantic forest of Rio de Janeiro, Callithrix aurita (É. Geoffroy in Humboldt, 1812) is a native species vulnerable to extinction and C. jacchus (Linnaeus, 1758) and C. penicillata (É. Geoffroy, 1812) are invasive species. The major threats to the native species are habitat degradation and hybridization, although there are currently no genetic data about natural hybrids available. Previous studies have revealed that species of the Callithrix genus are extremely homogeneous in their karyotypes with the exceptions of the morphology and size of the Y chromosome and its nucleolar organizer region (NOR) banding pattern. Three male marmosets captured in the wild in Guapimirim municipality, Rio de Janeiro, Brazil, considered as possible hybrids between C....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Marmosets; Y-chromosome; Karyotype; Hybridization.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0073-47212011000200002

Loss of Y-chromosome does not correlate with age at onset of head and neck carcinoma: a case-control study
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Silva Veiga,L.C.; Bérgamo,N.A.; Reis,P.P.; Kowalski,L.P.; Rogatto,S.R.
Loss of Y-chromosome has been correlated with older age in males. Furthermore, current evidence indicates that Y-chromosome loss also occurs in several human tumors, including head and neck carcinomas. However, the association between Y nullisomy and the occurrence of neoplasias in elderly men has not been well established. In the present study, the association between Y-chromosome loss and head and neck carcinomas was evaluated by comparison to cells from peripheral blood lymphocytes and normal mucosa of cancer-free individuals matched for age using dual-color fluorescence in situ hybridization. Twenty-one patients ranging in age from 28 to 68 years were divided into five-year groups for comparison with 16 cancer-free individuals matched for age. The...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fluorescence in situ hybridization; Y-chromosome; Chromosomal abnormalities; Head and neck cancer.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000200013