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慢性子宮内膜炎を呈したホルスタイン種雌牛にみられた牛白血病の1症例 OAK
竹内, 俊彦; 吉本, 薫; 駒形, 真; 福中, 守人; 古林, 与志安; 松本, 高太郎; 猪熊, 壽; TAKEUCHI, Toshihiko; YOSHIMOTO, Kaoru; KOMAGATA, Makoto; FUKUNAKA, Morito; KOBAYASHI, Yoshiyasu; MATSUMOTO, Kotaro; INOKUMA, Hisashi.
5歳5カ月齢のホルスタイン種雌牛が,発熱,食欲不振及び胎盤停滞を呈した.悪露排出及び子宮の腫脹は治療で改善がみられなかった.体表リンパ節の腫大はみられなかったが,直腸検査で子宮の硬結を認めたため,牛白血病を疑った.病理解剖では腹腔内リンパ節の腫大,胃漿膜面の腫瘤形成及び子宮壁の肥厚が認められた.また,組織所見ではこれら組織へのリンパ球様腫瘍細胞の浸潤が認められた.腫瘍細胞はB細胞マーカー陽性であった.牛白血病ウイルス(BLV)抗体は陰性であったが,末梢血のBLVプロウイルス検査では陽性が確認され,本症例におけるBLVの関与が示唆された. A 5-year-5-month old Holstein cow was presented with fever, anorexia, and retained placenta. Postnatal vaginal discharge and enlargement of the uterus did not improve after treatment. Although the superficial lymph nodes were not enlarged, enzootic bovine leukosis was suspected because of the enlarged and indurated uterus. An autopsy revealed enlargement of most abdominal lymph nodes, tumor mass formation on the omasum and abomasum, and thickening of the uterine wall. Histologically, there...
Palavras-chave: 牛白血病ウイルス; 慢性子宮内膜炎; 地方病性牛白血病; Bovine leukosis virus; Chronic endometritis; Enzootic bovine leukosis.
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3555
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ウマの胃排出能に対するクエン酸モサプリドの促進効果(内科学) OAK
OKAMURA, Koichi; SASAKI, Naoki; FUKUNAKA, Morito; YAMADA, Haruo; INOKUMA, Hisashi; 佐々木, 直樹; 猪熊, 壽.
The prokinetic effect of the 5-HT4 receptor agonist mosapride was evaluated in seven healthy thoroughbreds. Mosapride was orally administerd at doses of 0.5, 1.0 or 1.5 mg/kg. The breath 13CO2/12CO2 rate (Δ13CO2), an indirect indicator for the rate of gastric empting, was measured at appropriate points for 4 hr after drug administration. There was a significant increase compared with the control value at 15, 20 and 165 min for 0.5 mg/kg, 30 min at 1.0 mg/kg and 165 min for 1.5 mg/kg. The results suggest that mosapride may facilitate the gastric emptying in horses.
Palavras-chave: Equine; Gastric emptying rate; Mosapride citrate.
Ano: 2008 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4019
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Evaluation of Techniques That Measure Hydrogen and Methane Levels in Breaths of Horses with Gastrointestinal Diseases OAK
SASAKI, Naoki; FUKUNAKA, Morito; YAMADA, Haruo; SENBA, Hiroyuki; HIGUCHI, Tohru; 佐々木, 直樹.
Techniques for measuring hydrogen (H2) and methane (CH4) levels in breaths were assessed in horses with gastrointestinal (GI) diseases. A total of 31 horses were studied: 11 healthy horses (Group A), 10 horses with GI diseases (Group B), and 10 horses with diseases without GI involvement (Group C). Expired gases were measured using gas chromatography. CH4 levels in Group A were significantly lower than those in Group B. In Group B, CH4 levels were significantly higher after treatment. Fluctuations in H2 and CH4 levels in breath were associated with changes in GI function.
Palavras-chave: Equine; Hydrogen; Methane.
Ano: 2006 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3102
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