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Silver and gold nanoparticles from tannic acid: synthesis, characterization and evaluation of antileishmanial and cytotoxic activities Anais da ABC (AABC)
LOPES,LOURDES C.S.; BRITO,LUCAS M.; BEZERRA,THAYLLAN T.; GOMES,KLEYTON N.; CARVALHO,FERNANDO A. DE A.; CHAVES,MARIANA HELENA; CANTANHÊDE,WELTER.
Abstract Gold (Au0) and silver (Ag0) nanoparticles were synthesized using tannic acid (TA) as both reducing and stabilizer. Nanoparticles formation, stability, and interaction with TA were compared to citrate-coated nanoparticles and monitored by UV-Vis, zeta potential, and transmission electron microscopy. TA coating resulted in a red-shift and broadening of bands compared to citrate-coated nanoparticles (NPs-Cit). AgNPs-TA and AuNPs-TA are negatively charged with mean surface charge of -29.4 mV and -29.6 mV, respectively. TEM images showed polydispersety of AuNPs-TA (6-42 nm) and aggregation of AgNPs-TA (12-71 nm). In vitro assays of Leishmania amazonensis promastigotes showed an increment of antileishmanial activity for AgNPs-TA in relation to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Green synthesis; Leishmaniasis; Metallic nanoparticles; Tannic acid.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602679
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