Data/hora: 26/07/2024 22:45:19

Provedor de dados: 	Genetics and Molecular Biology	
País: 	Brazil	
Título: 	Patterns of molecular evolution in pathogenesis-related proteins	
Autores: 	Scherer,Nicole M.; Thompson,Claudia E.; Freitas,Loreta B.; Bonatto,Sandro L.; Salzano,Francisco M.	
Data: 	2005-12-01	
Ano: 	2005	
Palavras-chave: 	Pathogenesis-related proteins; PRs; Molecular variability; Positive selection; Maximum-likelihood methods.	
Resumo: 	The genes encoding 13 classes of pathogenesis-related (PR) proteins were examined for positive selection using maximum-likelihood (ML) models of codon substitution. The study involved 194 sequences from 54 species belonging to 37 genera. Although the sizes of the sequences examined varied from 237 bp for PR12 to 1,110 bp for PR7, most classes (9 out of 13) contained sequences made up of more than 400 nucleotides. Signs of positive selection were obtained for sites in PR proteins 4, 6, 8, 9 and 15 using an ML-based Bayesian method and likelihood ratio tests. These results confirm the importance of positive selection in proteins related to defense mechanisms already observed in a wide array of organisms.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500001	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572005000500001	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.28 n.4 2005	
Fonte: 	info:eu-repo/semantics/openAccess