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Diaz,Ricardo Sobhie; Sucupira,Maria Cecilia A; Vergara,Tania RC; Brites,Carlos; Bianco,Rosana Del; Bonasser Filho,Francisco; Colares,Geova Keny B; Portela,Estevão; Cherman,Lia Adler; Barcelos,Nemora Tregnago; Tupinambas,Unai; Turcato Jr,Gilberto; Allamasey,Lisa; Bacheler,Lee; Tuohy,Martin. |
OBJECTIVE: To investigates how the use of HIV-1 resistance tests influences physician decision-making. METHODS: Ten experienced reference physicians from the Brazilian Network for Drug Resistance each received ten patients' case histories. The selected patients had experienced at least two virological failures. First, reference physicians were asked to empirically select a new regimen for each patient. Second, after genotype report (ViroSeq 2.6) was provided, and physicians were again asked to select a new regimen considering this additional information. Finally, they were asked to select a regimen after receiving a virtual phenotype result (vircoTYPE 3.9.00). RESULTS: In 79% of the cases, physicians changed their empirical choice of regimen after... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Genotype; Virtual phenotype; Antiretroviral resistance; Brazil. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500011 |
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Caterino-de-Araujo,Adele; Manuel,Rolanda Carmen Rafael; Bianco,Rosana Del; Santos-Fortuna,Elizabeth; Magri,Mariana Cavalheiro; Silva,Joyce Matie Kinoshita; Bastos,Rui. |
Human herpesvirus 8 (HHV-8), the etiological agent of Kaposi's sarcoma (KS), is endemic in parts of the sub-Saharan, and KS has increased concomitantly with the HIV/AIDS epidemic. In Mozambique (MZ), no data concerning HHV-8 infection was available, thus the main of this work was to investigate, for the first time, the presence of HHV-8 infection in Maputo, MZ. Latent and lytic HHV-8-specific antibodies were assessed in blood samples from 189 individuals from the Central Hospital of Maputo, MZ, using "in-house" immunofluorescence assays conducted in São Paulo, Brazil. The results obtained were analyzed according to socio-demographic and clinical variables using the Chi-square test and logistic regression. An HHV-8 seropositivity of 1.8% and 9.7% was... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Human herpesvirus 8 (HHV-8); Serology; Mozambique; Frequency; Kaposi's sarcoma. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300008 |
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Bianco,Rosana Del; Santos,Maria Silvia Biagioni; Ribeiro,Maria Clara Gianna Garcia; Viso,Ana Teresa Rodriguez; Carvalho,Valquíria. |
OBJECTIVE: To describe the clinical aspects of H1N1 among HIV coinfected patients seen at a reference center for AIDS treatment in São Paulo, Brazil. Design: Observational and prospective cohort study. METHODS: Descriptive study of clinical and laboratory investigation of HIV-infected patients with confirmed diagnosis of influenza A (H1N1) in 2009. We analyzed patients monitored in CRT/DST/AIDS, a specialized service for people living with HIV, located in São Paulo, Brazil. RESULTS: 108 individuals presented with symptoms of H1N1 infection at the CRT DST/AIDS in 2009. Eighteen patients (16.7%) had confirmation of the diagnosis of influenza A. Among the confirmed cases, ten (55.6%) were hospitalized and eight (44.4%) were outpatients. Dyspnea was present in... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Influenza A virus; H1N1 subtype HIV acquired immunodeficiency syndrome. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000200015 |
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