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Imunogenicidade da proteína M recombinante de Streptococcus equi subsp. equi coadministrada com um adjuvante molecular Arq. Bras. Med. Vet. Zootec.
Maciel,L.F.; Magalhães,C.G.; Moraes,C.M.; Rosa,M.C.; Mendonça,M.; Moreira,A.N.; Dummer,L.A.; Finger,P.F.; Ferreira,M.R.A.; Leite,F.P.L.; Conceição,F.R..
ABSTRACT The strangles is an infectious disease that affects horses from all ages and causes important economic losses in the equine-related business. The aim of this work was to evaluate the immunogenicity of the recombinant M protein from Streptococcus equi (rSeM) co-administered with the recombinant heat-labile enterotoxin B subunit from Escherichia coli (rLTB) in mice and horses. A total of 72 female Balb-c mice were divided into eight groups and 18 horses were divided into six groups. The animals were inoculated by intramuscular (IM) or intranasal (IN) routes with different treatments of rSeM, rLTB and/or Al(OH)3. The results obtained in both species, independent of administration routes, demonstrated that rSeM + rLTB had higher levels of specific...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Garrotilho; Streptococcus equi; RSeM e rLTB.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000501351
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Distribution of the stx1 and stx2 genes in Escherichia coli isolated from milk cattle according to season, age, and production scale in southwestern region of Goiás, Brazil Arq. Bras. Med. Vet. Zootec.
Ferreira,M.R.A.; Stella,A.E.; Freitas-Filho,E.G.; Silva,T.S.; Nascimento,K.A.; Pinto,J.F.N.; Dias,M.; Moreira,C.N..
ABSTRACT This study determined the distribution of stx1 and stx2 genes in Escherichia coli isolated from dairy herds with regard to animal age, season, and farm production-scale, and analyzed the phylogenetic distribution of the groups A, B1, B2, and D of 276 isolates of bovine feces Shiga toxin-producing E. coli (STEC). The stx1 profile was the most common, detected in 20.4% (202/990) of the isolates, followed by stx2 (4.54%, 45/990) and stx1+stx2 (2.92%, 29/990). The stx1 gene was detected more frequently in calves than in adult animals. In the dry season (winter), the presence of stx1+stx2 profile in cattle feces was higher than in the rainy season (summer), while no significant changes were observed between seasons for the stx1 and stx2 profiles. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Shiga toxin-producing Escherichia coli (STEC); Phylogenetic STEC groups; STEC reservoirs Stx1; Stx2.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000601807
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