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Development of a mouse computational model for MCNPx based on Digimouse (r) images and dosimetric assays BJPS
Mendes,Bruno Melo; Almeida,Iassudara Garcia de; Trindade,Bruno Machado; Fonseca,Telma Cristina Ferreira; Campos,Tarcísio Passos Ribeiro de.
ABSTRACT The aim of this study was to create and test a new mice 3D-voxel phantom named DM_BRA for mice and human first-estimation radiopharmaceutical dosimetry. Previously, the article reviews the state-of-art in animal model development. Images from Digimouse CT database were used in the segmentation and on the generation of the voxelized phantom. Simulations for validation of the DM_BRA model was performed at 0.015, 0.1, 0.5, 1 and 4 MeV photons with heart-source. Specific Absorbed Fractions (SAF) data were compared with literature data. The organ masses of DM_BRA correlated well with existing models based on the same dataset; however, few small organ masses hold significant variations. The SAF data in most simulated cases were statistically equal to a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dosimetry/assay; Mouse phantom/tests; MCNPx Monte Carlo code Computational studies..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100622
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