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| Han,C; Ye,F; Shen,X; Liu,D; He,F; Wei,S; Xu,H; Li,L; Liu,H. |
| ABSTRACTThis study aimed at examining the effect of overfeeding on the activity of the mTOR pathway in the liver and muscle tissues of Gang geese. Eighty healthy male Gang geese were reared under the same feeding conditions, and were divided at 14 weeks of age into a control group and an overfed group. All birds were slaughtered after three weeks of over feeding. Gene expression and protein content of several genes involved in the mTOR pathway were evaluated. The results showed that the gene expression of mTOR, raptor, and rictor, and the protein contents of mTOR and PI3K were higher in liver, breast muscle, and leg muscle of the overfed group than that of control group. However, the S6K expression level was clearly lower in the liver of the overfed group... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Goose; MTOR pathway; Overfeeding; Tissues. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000300293 |
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| Xu,HY; Tang,H; Pan,ZX; Li,L; Han,CC; Liu,HH; He,H; Kang,B; Hu,JW; Xia,L; Wang,Y; Wang,JW. |
| ABSTRACT The carbohydrate response element-binding protein (ChREBP) is an important nuclear factor that regulates glycolysis and de novo lipogenesis. However, the role of ChREBP in fatty liver development in geese remains unclear. In order to understand the function of ChREBP in lipid metabolism of geese, we first cloned the complete cDNA of the ChREBP of the Sichuan White goose (Anser cygnoides) using RT-PCR, 5’ RACE and 3’ RACE, and analyzed goose ChREBP expression in nine different tissues using real-time PCR technology. The results showed that the goose ChREBP CDS consists of 945bp nucleotides that encode 314 amino acids, and the sequence has high similarities with the swan goose (Anser cygnoides domesticus) and duck (Anas platyrhynchos) sequences,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ChREBP; Expression profile; Molecular cloning; RACE; Sichuan White Goose. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2017000400615 |
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| Tang,B; Yang,C; Hu,S; Sun,W; Pan,Z; Li,L; Wang,J. |
| ABSTRACT Over-accumulation of triglycerides (TGs) in goose hepatocytes leads to the formation of fatty acid liver. Phosphoenolpyruvate carboxylase kinase 1 (PEPCK) is regarded as the rate-limiting enzyme for gluconeogenesis, and there is evidence that PEPCK is involved in regulating hepatic glucolipid metabolism. Hence, we proposed that PEPCK may have a role in goose hepatic steatosis. To test our hypothesis, the present study was conducted to firstly determine the sequence characteristics of goose PEPCK and then to explore its role in overfeeding-induced fatty liver. Our results showed that goose PEPCK encodes a 622-amino-acids protein that contains highly conserved oxaloacetate-binding domain, kinase-1 and kinase-2 motifs. PEPCK had higher mRNA levels in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Goose; PEPCK; Sequence characteristics; Hepatic steatosis; Primary hepatocytes. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2020000400302 |
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| Liu,H; Liu,J; Zhang,T; Li,L; Wang,J; Han,C; He,H. |
| ABSTRACT The bursa of Fabricius (BF) is the central humoral immune organ unique to birds. The present study investigated the possible difference on a molecular level between two duck breeds. The digital gene expression profiling (DGE) technology was used to enrich the differentially expressed genes (DEGs) in BF between the Jianchang and Nonghua-P strains of ducks. DGE data identified 195 DEGs in the bursa. Gene Ontology (GO) analysis suggested that DEGs were mainly enriched in the metabolic pathways and ribosome components. Pathways analysis identified the spliceosome, RNA transport, RNA degradation process, Jak-STAT signaling pathway, TNF signaling pathway and B cell receptor signaling pathway. The results indicated that the main difference in the BF... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bursa of Fabricius; Gene ontology; Duck; Digital gene expression profiling.. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2018000100169 |
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| Huang,R; Li,L; Song,B; Lyu,Y; Wu,B. |
| ABSTRACT This study explores the differences of appearance and the digestive systems of two birds (Lonchura striata and Copsychus saularis), which have the same eating pattern in staple ingredients. Each bird was caught naturally and euthanized in appropriate manner, followed by morphology survey on bill, duodenum, jejunum, ileum and appearance of the body parts such as Culmen, Claw, Wing, Tarsus, Toe and Tail. The results showed that the appearance feature between them presented significant differences in the beak length, wing length and tail length, which were correlated to their staple feeding habits. In addition, in the digestive system, the length of duodenum and duodenal indexes showed significant differences (p<0.05 or p<0.01), which was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lonchura striata; Copsychus saularis; Feature parameters; Digestive system; Feeding habits. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2020000400309 |
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